By 2020, chronic obstructive pulmonary disease (COPD) will be the third cause of mortality.
Extrapulmonary comorbidities influence the prognosis of patients with COPD. Tobacco …

In 9–20% of cases, Sjögren's syndrome is associated with various respiratory symptoms.
The most typical manifestations are chronic interstitial lung disease (ILD) and …

The clinical expression of idiopathic pulmonary fibrosis (IPF) is directly related to multiple
alterations in lung function. These alterations derive from a complex disease process …

Rationale: Pulmonary fibrosis is a devastating as yet untreatable disease. We previously
investigated the endogenous mediators released on lung injury and showed that uric acid is …

Background Given the phenotypic similarities between rheumatoid arthritis (RA)–associated
interstitial lung disease (ILD)(hereafter, RA-ILD) and idiopathic pulmonary fibrosis, we …

Question addressed by the study Methotrexate (MTX) is a key anchor drug for rheumatoid
arthritis (RA) management. Fibrotic interstitial lung disease (ILD) is a common complication …

Ectopic formation of secondary lymphoid tissue is initiated by the local attraction of naive T
and B cells. In this study, we describe a novel type of organized lymphoid structure in the …

Despite its high prevalence and mortality, little is known about the pathogenesis of
rheumatoid arthritis-associated interstitial lung disease (RA-ILD). Given that familial …

Introduction Idiopathic pulmonary fibrosis (IPF) has an unpredictable course corresponding
to various profiles: stability, physiological disease progression and rapid decline. A minority …

Telomerase reverse transcriptase (TERT) or telomerase RNA (TERC) gene mutation is a
major monogenic cause of pulmonary fibrosis. Sequencing of TERT/TERC genes is …