Coexistence of OSA may compensate for sleep related reduction in neural respiratory drive in patients with COPD

BT He, G Lu, SC Xiao, R Chen, J Steier, J Moxham… - Thorax, 2017 - thorax.bmj.com
Background The mechanisms underlying sleep-related hypoventilation in patients with
coexisting COPD and obstructive sleep apnoea (OSA), an overlap syndrome, are …

Neural respiratory drive and arousal in patients with obstructive sleep apnea hypopnea

SC Xiao, BT He, J Steier, J Moxham, MI Polkey… - Sleep, 2015 - academic.oup.com
Abstract Study Objectives: It has been hypothesized that arousals after apnea and hypopnea
events in patients with obstructive sleep apnea are triggered when neural respiratory drive …

Effect of expiratory load on neural inspiratory drive

SC Xiao, YR Lu, HX Guo, ZH Qiu… - Chinese Medical …, 2012 - journals.lww.com
Background Neural respiratory drive is usually measured during inspiration, even in patients
with chronic obstructive pulmonary disease (COPD) in whom the primary physiological …

Absence of dynamic hyperinflation during exhaustive exercise in severe COPD reflects submaximal IC maneuvers rather than a nonhyperinflator phenotype

YM Luo, ZH Qiu, Y Wang, BT He… - Journal of Applied …, 2020 - journals.physiology.org
Approximately 20% of chronic obstructive pulmonary disease (COPD) patients have been
considered to have a “nonhyperinflator phenotype.” However, this judgment depends on …