[HTML][HTML] Role of the adaptive immune response in sepsis
J Brady, S Horie, JG Laffey - Intensive care medicine experimental, 2020 - Springer
Sepsis is a syndrome of shock and dysfunction of multiple vital organs that is caused by an
uncontrolled immune response to infection and has a high mortality rate. There are no …
uncontrolled immune response to infection and has a high mortality rate. There are no …
[HTML][HTML] Emerging pharmacological therapies for ARDS: COVID-19 and beyond
ARDS, first described in 1967, is the commonest form of acute severe hypoxemic respiratory
failure. Despite considerable advances in our knowledge regarding the pathophysiology of …
failure. Despite considerable advances in our knowledge regarding the pathophysiology of …
[HTML][HTML] Cell therapy in acute respiratory distress syndrome
S Horie, HE Gonzalez, JG Laffey… - Journal of thoracic …, 2018 - ncbi.nlm.nih.gov
Acute respiratory distress syndrome (ARDS) is driven by a severe pro-inflammatory
response resulting in lung damage, impaired gas exchange and severe respiratory failure …
response resulting in lung damage, impaired gas exchange and severe respiratory failure …
Human mesenchymal stromal cells decrease the severity of acute lung injury induced by E. coli in the rat
J Devaney, S Horie, C Masterson, S Elliman, F Barry… - Thorax, 2015 - thorax.bmj.com
Background Mesenchymal stromal cells (MSCs) demonstrate considerable promise in
preclinical acute respiratory distress syndrome models. We wished to determine the efficacy …
preclinical acute respiratory distress syndrome models. We wished to determine the efficacy …
Demographics, management and outcome of females and males with acute respiratory distress syndrome in the LUNG SAFE prospective cohort study
BA McNicholas, F Madotto, T Pham… - European …, 2019 - Eur Respiratory Soc
Rationale We wished to determine the influence of sex on the management and outcomes in
acute respiratory distress syndrome (ARDS) patients in the Large Observational Study to …
acute respiratory distress syndrome (ARDS) patients in the Large Observational Study to …
Syndecan-2–positive, bone marrow–derived human mesenchymal stromal cells attenuate bacterial-induced acute lung injury and enhance resolution of ventilator …
C Masterson, J Devaney, S Horie, L O'Flynn… - …, 2018 - pubs.asahq.org
Abstract What We Already Know about This Topic Human mesenchymal stromal cells
diminish injury and enhance recovery and repair after ventilator-induced lung injury in …
diminish injury and enhance recovery and repair after ventilator-induced lung injury in …
[HTML][HTML] Umbilical cord-derived CD362+ mesenchymal stromal cells for E. coli pneumonia: impact of dose regimen, passage, cryopreservation, and antibiotic therapy
S Horie, C Masterson, J Brady, P Loftus… - Stem cell research & …, 2020 - Springer
Abstract Background Mesenchymal stromal cells (MSCs) demonstrate considerable promise
for acute respiratory distress syndrome (ARDS) and sepsis. However, standard approaches …
for acute respiratory distress syndrome (ARDS) and sepsis. However, standard approaches …
Stem cell therapy for acute respiratory distress syndrome: a promising future?
S Horie, C Masterson, J Devaney… - Current Opinion in …, 2016 - journals.lww.com
Stem cell therapy for acute respiratory distress syndrome: a... : Current Opinion in Critical Care
Stem cell therapy for acute respiratory distress syndrome: a promising future? : Current …
Stem cell therapy for acute respiratory distress syndrome: a promising future? : Current …
[HTML][HTML] Fresh and cryopreserved human umbilical-cord-derived mesenchymal stromal cells attenuate injury and enhance resolution and repair following ventilation …
S Horie, H Gonzalez, J Brady, J Devaney… - International Journal of …, 2021 - mdpi.com
Background: Ventilator-induced lung injury (VILI) frequently worsens acute respiratory
distress syndrome (ARDS) severity. Human mesenchymal stem/stromal cells (MSCs) offer …
distress syndrome (ARDS) severity. Human mesenchymal stem/stromal cells (MSCs) offer …
[HTML][HTML] Cytokine pre-activation of cryopreserved xenogeneic-free human mesenchymal stromal cells enhances resolution and repair following ventilator-induced lung …
Background Human mesenchymal stem/stromal cells (hMSCs) represent a promising
therapeutic strategy for ventilator-induced lung injury (VILI) and acute respiratory distress …
therapeutic strategy for ventilator-induced lung injury (VILI) and acute respiratory distress …