Ultrastructural study shows morphologic features of apoptosis and para-apoptosis in megakaryocytes from patients with idiopathic thrombocytopenic purpura
EJ Houwerzijl, NR Blom, JJL van der Want… - Blood, 2004 - ashpublications.org
To investigate whether altered megakaryocyte morphology contributes to reduced platelet
production in idiopathic thrombocytopenic purpura (ITP), ultrastructural analysis of …
production in idiopathic thrombocytopenic purpura (ITP), ultrastructural analysis of …
β -Adrenoceptor-mediated Inhibition of IFN- γ , IL-3, and GM-CSF mRNA Accumulation in Activated Human T Lymphocytes Is Solely Mediated by the β2 …
P Borger, Y Hoekstra, MT Esselink… - American journal of …, 1998 - atsjournals.org
Cytokine gene expression in T lymphocytes is a strictly regulated process, involving both
stimulatory and inhibitory signals. β-Adrenoceptor (βAR) agonists are widely used in the …
stimulatory and inhibitory signals. β-Adrenoceptor (βAR) agonists are widely used in the …
Lymphocyte-stimulation tests and patch tests to carbamazepine hypersensitivity.
J Houwerzijl, GC De Gast, JP Nater… - Clinical and …, 1977 - ncbi.nlm.nih.gov
Seven cases of severe hypersensitivity to carbamazepine (Tegretol) were described in
patients with epilepsy or trigeminal neuralgia. Clinical manifestations consisted of fever …
patients with epilepsy or trigeminal neuralgia. Clinical manifestations consisted of fever …
The release of endotoxin from antibiotic-treated Escherichia coli and the production of tumour necrosis factor by human monocytes
ASM Dofferhoff, MT Esselink… - Journal of …, 1993 - academic.oup.com
The influence of antibiotic-induced release of endotoxin from in-vitro grown Escherichia coli
on the production of tumour necrosis factor-α (TNF) by human monocytes was studied …
on the production of tumour necrosis factor-α (TNF) by human monocytes was studied …
Increased peripheral platelet destruction and caspase-3–independent programmed cell death of bone marrow megakaryocytes in myelodysplastic patients
EJ Houwerzijl, NR Blom, JJL van der Want, H Louwes… - Blood, 2005 - ashpublications.org
To investigate underlying mechanisms of thrombocytopenia in myelodysplastic syndrome
(MDS), radiolabeled platelet studies were performed in 30 MDS patients with platelet counts …
(MDS), radiolabeled platelet studies were performed in 30 MDS patients with platelet counts …
The spontaneous expression of interleukin-1 beta and interleukin-6 is associated with spontaneous expression of AP-1 and NF-kappa B transcription factor in acute …
WH Dokter, L Tuyt, SJ Sierdsema, MT Esselink… - Leukemia, 1995 - europepmc.org
The nature of the spontaneous expression of cytokines that is observed in blasts of some
AML patients is unclear. We studied whether or not the spontaneous expression of IL-1 beta …
AML patients is unclear. We studied whether or not the spontaneous expression of IL-1 beta …
Stem cell factor synergistically enhances thrombopoietin‐induced STAT5 signaling in megakaryocyte progenitors through JAK2 and src kinase
AL Drayer, AK Boer, EL Los, MT Esselink… - Stem Cells, 2005 - academic.oup.com
Stem cell factor (SCF) has a potent synergistic effect during megakaryopoiesis when
administered in combination with the major megakaryocytic cytokine, thrombopoietin (TPO) …
administered in combination with the major megakaryocytic cytokine, thrombopoietin (TPO) …
A dual function for p38 MAP kinase in hematopoietic cells: involvement in apoptosis and cell activation
KU Birkenkamp, WHA Dokter, MT Esselink, LJC Jonk… - Leukemia, 1999 - nature.com
In the present study we examined in more detail the dual role of the c-JUN N-terminal kinase
(JNK) and p38 stress-activated protein kinase pathways in mediating apoptosis or cellular …
(JNK) and p38 stress-activated protein kinase pathways in mediating apoptosis or cellular …
Divergent effects of interleukin-4 (IL-4) on the granulocyte colony-stimulating factor and IL-3-supported myeloid colony formation from normal and leukemic bone …
E Vellenga, JT De Wolf, JA Beentjes, MT Esselink… - 1990 - ashpublications.org
Abstract Human recombinant interleukin-4 (IL-4) was studied for its effects on myeloid
progenitor cells from normal and leukemic bone marrow cells in the presence and absence …
progenitor cells from normal and leukemic bone marrow cells in the presence and absence …
[HTML][HTML] Interleukin-4 inhibits the lipopolysaccharide-induced expression of c-jun and c-fos messenger RNA and activator protein-1 binding activity in human …
WHA Dokter, MT Esselink, MR Halie, E Vellenga - Blood, 1993 - Elsevier
We studied the effect of interleukin-4 (IL-4) on the lipopolysaccharide (LPS) induction of two
immediate early genes c-fos and c-jun. These genes encode proteins that form the dimeric …
immediate early genes c-fos and c-jun. These genes encode proteins that form the dimeric …