Consequences of telomere replication failure: the other end-replication problem
KA Brenner, J Nandakumar - Trends in biochemical sciences, 2022 - cell.com
Telomeres are chromosome-capping structures that protect ends of the linear genome from
DNA damage sensors. However, these structures present obstacles during DNA replication …
DNA damage sensors. However, these structures present obstacles during DNA replication …
Human POT1 protects the telomeric ds-ss DNA junction by capping the 5′ end of the chromosome
VM Tesmer, KA Brenner, J Nandakumar - Science, 2023 - science.org
Protection of telomeres 1 (POT1) is the 3′ single-stranded overhang-binding telomeric
protein that prevents an ataxia telangiectasia and Rad3–related (ATR) DNA damage …
protein that prevents an ataxia telangiectasia and Rad3–related (ATR) DNA damage …
Acute graft-versus-host disease following lung transplantation in a patient with a novel TERT mutation
Familial pulmonary fibrosis is associated with loss-of-function mutations in telomerase
reverse transcriptase (TERT) and short telomeres. Interstitial lung diseases have become …
reverse transcriptase (TERT) and short telomeres. Interstitial lung diseases have become …
[PDF][PDF] CONFLICT OF INTEREST
EL Niero, WC Fok, AT Vessoni, KA Brenner, L FZ - scholar.archive.org
Telomere attrition is a risk factor for end-stage liver disease. Due to a lack of adequate
models and intrinsic difficulties in studying telomerase in physiologically relevant cells, the …
models and intrinsic difficulties in studying telomerase in physiologically relevant cells, the …
Telomere dysfunction represses HNF4α leading to impaired hepatocyte development and function
EL Niero, WC Fok, AT Vessoni, KA Brenner… - bioRxiv, 2019 - biorxiv.org
Telomere attrition is a risk factor for end-stage liver disease. Due to a lack of adequate
models and intrinsic difficulties in studying telomerase in physiologically relevant cells, the …
models and intrinsic difficulties in studying telomerase in physiologically relevant cells, the …