Progressive fibrotic interstitial lung diseases (ILDs) are characterised by major reductions in
quality of life and survival and have similarities to certain malignancies. However, palliative …

The burden of chronic obstructive pulmonary disease (COPD) in the USA continues to grow.
Although progress has been made in the the development of diagnostics, therapeutics, and …

Background Idiopathic pulmonary fibrosis (IPF) is a chronic progressive fibrotic lung disease
associated with substantial morbidity and mortality. The objective of this study was to …

Background: There is controversy about how to manage requests by patients or surrogates
for treatments that clinicians believe should not be administered. Purpose: This multisociety …

Importance Current prediction models of mortality in idiopathic pulmonary fibrosis (IPF),
which are based on clinical and physiological parameters, have modest value in predicting …

Rationale: Idiopathic pulmonary fibrosis (IPF) is a lethal lung disease of unknown etiology
with a variable and unpredictable course. Objectives: The aim of this study was to identify …

COPD is the fourth leading cause of death in the United States and is a serious respiratory
illness characterized by years of progressively debilitating breathlessness, high prevalence …

Rationale: The molecular mechanisms underlying acute exacerbations of idiopathic
pulmonary fibrosis (IPF) are poorly understood. We studied the global gene expression …

We aimed to identify peripheral blood mononuclear cell (PBMC) gene expression profiles
predictive of poor outcomes in idiopathic pulmonary fibrosis (IPF) by performing microarray …

Background: Evidence-based guidelines are needed for effective delivery of home oxygen
therapy to appropriate patients with chronic obstructive pulmonary disease (COPD) and …