Acute exacerbation of idiopathic pulmonary fibrosis. An international working group report

HR Collard, CJ Ryerson, TJ Corte… - American journal of …, 2016 - atsjournals.org
Acute exacerbation of idiopathic pulmonary fibrosis has been defined as an acute, clinically
significant, respiratory deterioration of unidentifiable cause. The objective of this …

Idiopathic pulmonary fibrosis: Disease mechanisms and drug development

P Spagnolo, JA Kropski, MG Jones, JS Lee… - Pharmacology & …, 2021 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a chronic progressive disease of unknown cause
characterized by relentless scarring of the lung parenchyma leading to reduced quality of life …

Does chronic microaspiration cause idiopathic pulmonary fibrosis?

JS Lee, HR Collard, G Raghu, MP Sweet… - The American journal of …, 2010 - Elsevier
Idiopathic pulmonary fibrosis is a diffuse fibrotic lung disease of unknown etiology with no
effective treatment. Emerging data support a role for chronic microaspiration (ie, subclinical …

A multidimensional index and staging system for idiopathic pulmonary fibrosis

B Ley, CJ Ryerson, E Vittinghoff, JH Ryu… - Annals of internal …, 2012 - acpjournals.org
Background: Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease with an
overall poor prognosis. A simple-to-use staging system for IPF may improve prognostication …

The effect of surface charge on in vivo biodistribution of PEG-oligocholic acid based micellar nanoparticles

K Xiao, Y Li, J Luo, JS Lee, W Xiao, AM Gonik… - Biomaterials, 2011 - Elsevier
To systematically elucidate the effect of surface charge on the cellular uptake and in vivo fate
of PEG-oligocholic acid based micellar nanoparticles (NPs), the distal PEG termini of …

An official European Respiratory Society/American Thoracic Society research statement: interstitial pneumonia with autoimmune features

A Fischer, KM Antoniou, KK Brown… - European …, 2015 - Eur Respiratory Soc
Many patients with an idiopathic interstitial pneumonia (IIP) have clinical features that
suggest an underlying autoimmune process but do not meet established criteria for a …

In vitro and in vivo gene therapy vector evolution via multispecies interbreeding and retargeting of adeno-associated viruses

D Grimm, JS Lee, L Wang, T Desai, B Akache… - Journal of …, 2008 - Am Soc Microbiol
Adeno-associated virus (AAV) serotypes differ broadly in transduction efficacies and tissue
tropisms and thus hold enormous potential as vectors for human gene therapy. In reality …

Usual interstitial pneumonia in rheumatoid arthritis-associated interstitial lung disease

EJ Kim, BM Elicker, F Maldonado… - European …, 2010 - Eur Respiratory Soc
Interstitial lung disease is a common manifestation of rheumatoid arthritis; however, little is
known about factors that influence its prognosis. The aim of the present study was to …

Gastroesophageal reflux therapy is associated with longer survival in patients with idiopathic pulmonary fibrosis

JS Lee, JH Ryu, BM Elicker, CP Lydell… - American journal of …, 2011 - atsjournals.org
Rationale: Gastroesophageal reflux (GER) is highly prevalent in patients with idiopathic
pulmonary fibrosis (IPF). Chronic microaspiration secondary to GER may play a role in the …

Anti-acid treatment and disease progression in idiopathic pulmonary fibrosis: an analysis of data from three randomised controlled trials

JS Lee, HR Collard, KJ Anstrom… - The Lancet …, 2013 - thelancet.com
Background Abnormal acid gastro-oesophageal reflux is common in patients with idiopathic
pulmonary fibrosis (IPF) and is considered a risk factor for development of IPF. Retrospective …