User profiles for "author:John E Hokanson"

John E Hokanson

Professor of Epidemiology, University of Colorado Anschutz Medical Campus
Verified email at cuanschutz.edu
Cited by 30514

Dyslipidemia of central obesity and insulin resistance

JD Brunzell, JE Hokanson - Diabetes care, 1999 - search.proquest.com
CENTRAL OBESITY-J. Vague (9) first documented central obesity as an adverse health
factor in the early 1950s when he described the android and gynoid forms of obesity …

Characterization of low-density lipoprotein subclasses: méthodologie approaches and clinical relevance

MA Austin, JE Hokanson… - Current opinion in …, 1994 - journals.lww.com
Emerging evidence suggests that subclasses of LDL, characterized by variations in density,
size, and chemical composition of LDL particles, are of important clinical significance …

Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use

M Liu, Y Jiang, R Wedow, Y Li, DM Brazel, F Chen… - Nature …, 2019 - nature.com
Tobacco and alcohol use are leading causes of mortality that influence risk for many
complex diseases and disorders. They are heritable, and etiologically related, behaviors that …

Plasma triglyceride level is a risk factor for cardiovascular disease independent of high-density lipoprotein cholesterol level: a metaanalysis of population-based …

JE Hokanson, MA Austin - Journal of cardiovascular risk, 1996 - journals.sagepub.com
Objectives Despite nearly 40 years of research, the role of plasma triglyceride as a risk factor
for cardiovascular disease remains elusive. The objectives of the present study were to …

Genetic epidemiology of COPD (COPDGene) study design

EA Regan, JE Hokanson, JR Murphy… - COPD: Journal of …, 2011 - Taylor & Francis
Background: COPDGene is a multicenter observational study designed to identify genetic
factors associated with COPD. It will also characterize chest CT phenotypes in COPD …

Hypertriglyceridemia as a cardiovascular risk factor

JE Hokanson - The American journal of cardiology, 1998 - Elsevier
To determine the relation between plasma triglyceride levels and the risk of incident
cardiovascular disease, the semiquantitative techniques of meta-analysis were applied to 17 …

[HTML][HTML] Genetic diversity fuels gene discovery for tobacco and alcohol use

GRB Saunders, X Wang, F Chen, SK Jang, M Liu… - Nature, 2022 - nature.com
Tobacco and alcohol use are heritable behaviours associated with 15% and 5.3% of
worldwide deaths, respectively, due largely to broad increased risk for disease and injury …

CHRNA5 Risk Variant Predicts Delayed Smoking Cessation and Earlier Lung Cancer Diagnosis—A Meta-Analysis

LS Chen, RJ Hung, T Baker, A Horton… - Journal of the …, 2015 - academic.oup.com
Background: Recent meta-analyses show strong evidence of associations among genetic
variants in CHRNA5 on chromosome 15q25, smoking quantity, and lung cancer. This meta …

Association between telomere length and risk of cancer and non-neoplastic diseases: a Mendelian randomization study

PC Haycock, S Burgess, A Nounu, J Zheng… - JAMA …, 2017 - jamanetwork.com
Importance The causal direction and magnitude of the association between telomere length
and incidence of cancer and non-neoplastic diseases is uncertain owing to the susceptibility …

[HTML][HTML] Pulmonary arterial enlargement and acute exacerbations of COPD

JM Wells, GR Washko, MLK Han… - New England journal …, 2012 - Mass Medical Soc
Background Exacerbations of chronic obstructive pulmonary disease (COPD) are
associated with accelerated loss of lung function and death. Identification of patients at risk …