User profiles for "author:J J Byrnes"

John J Byrnes

Professor of Medicine, University of Miami
Verified email at med.miami.edu
Cited by 8933

AKI in hospitalized children: comparing the pRIFLE, AKIN, and KDIGO definitions

SM Sutherland, JJ Byrnes, M Kothari… - Clinical Journal of the …, 2015 - journals.lww.com
Results AKI incidences across the cohort according to pRIFLE, AKIN, and KDIGO were
51.1%, 37.3%, and 40.3%. Mortality was higher among patients with AKI across all …

Randomized comparison of allogeneic versus autologous mesenchymal stem cells for nonischemic dilated cardiomyopathy: POSEIDON-DCM trial

JM Hare, DL DiFede, AC Rieger, V Florea… - Journal of the American …, 2017 - jacc.org
Background: Although human mesenchymal stem cells (hMSCs) have been tested in
ischemic cardiomyopathy, few studies exist in chronic nonischemic dilated cardiomyopathy …

Treatment of thrombotic thrombocytopenic purpura with plasma

JJ Byrnes, M Khurana - New England journal of medicine, 1977 - Mass Medical Soc
Thrombotic thrombocytopenic purpura, the acute form of which is usually fatal, is
characterized clinically by thrombocytopenia, microangiopathic hemolytic anemia …

Dose comparison study of allogeneic mesenchymal stem cells in patients with ischemic cardiomyopathy (the TRIDENT study)

V Florea, AC Rieger, DL DiFede… - Circulation …, 2017 - Am Heart Assoc
Rationale: Cell dose and concentration play crucial roles in phenotypic responses to cell-
based therapy for heart failure. Objective: To compare the safety and efficacy of 2 doses of …

Thrombotic microangiopathies associated with drugs and bone marrow transplantation

JL Moake, JJ Byrnes - Hematology/Oncology Clinics, 1996 - hemonc.theclinics.com
Thrombotic thrombocytopenic purpura (TTP) is characterized by thrombocytopenia,
microangiopathic hemolytic anemia, central nervous system ischemia, and sometimes fever …

A new mammalian DNA polymerase with 3'to 5'exonuclease activity: DNA polymerase δ

JJ Byrnes, KM Downey, VL Black, AG So - Biochemistry, 1976 - ACS Publications
Materials and Methods 3H-Labeled deoxyribonucleoside triphosphates were pur-chased
from New England Nuclear Corp. or Amersham-Searle. Unlabeled deoxyribonucleoside …

Allogeneic mesenchymal stem cells ameliorate aging frailty: a phase II randomized, double-blind, placebo-controlled clinical trial

BA Tompkins, DL DiFede, A Khan… - … Series A: Biomedical …, 2017 - academic.oup.com
Background Aging frailty, characterized by decreased physical and immunological
functioning, is associated with stem cell depletion. Human allogeneic mesenchymal stem …

Mice deleted for fatty acid transport protein 5 have defective bile acid conjugation and are protected from obesity

B Hubbard, H Doege, S Punreddy, H Wu, X Huang… - Gastroenterology, 2006 - Elsevier
Background & Aims: Fatty Acid Transport Protein 5 (FATP5) is a liver-specific member of the
FATP/Slc27 family, which has been shown to exhibit both fatty acid transport and bile acid …

7 Thrombotic Thrombocytopenic Purpura and the Haemolytic-Uraemic Syndrome: Evolving Concepts of Pathogenesis and Therapy

JJ Byrnes, JL Moake - Clinics in haematology, 1986 - Elsevier
Thrombotic thrombocytopenic purpura (TTP) and the haemolytic-uraemic syndrome (HUS)
are dramatic examples of platelet thrombi in the microcirculation. In both TTP and the HUS …

Adolescent opioid exposure in female rats: transgenerational effects on morphine analgesia and anxiety-like behavior in adult offspring

JJ Byrnes, JA Babb, VF Scanlan, EM Byrnes - Behavioural brain research, 2011 - Elsevier
The use of narcotics by adolescent females is a growing problem, yet very little is known
about the long-term consequences for either the user or her future offspring. In the current …