Allergic Rhinitis and its Impact on Asthma (ARIA): achievements in 10 years and future needs
J Bousquet, HJ Schünemann, B Samolinski… - Journal of Allergy and …, 2012 - Elsevier
Allergic rhinitis (AR) and asthma represent global health problems for all age groups.
Asthma and rhinitis frequently coexist in the same subjects. Allergic Rhinitis and its Impact …
Asthma and rhinitis frequently coexist in the same subjects. Allergic Rhinitis and its Impact …
Clinical phenotypes of asthma
EH Bel - Current opinion in pulmonary medicine, 2004 - journals.lww.com
The classic phenotype of IgE-mediated asthma starting in childhood is now clearly defined.
However, many other phenotypes of asthma in childhood as well in adulthood are being …
However, many other phenotypes of asthma in childhood as well in adulthood are being …
Diagnosis and definition of severe refractory asthma: an international consensus statement from the Innovative Medicine Initiative (IMI)
Patients with severe refractory asthma pose a major healthcare problem. Over the last
decade it has become increasingly clear that, for the development of new targeted therapies …
decade it has become increasingly clear that, for the development of new targeted therapies …
International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma
Severe or therapy-resistant asthma is increasingly recognised as a major unmet need. A
Task Force, supported by the European Respiratory Society and American Thoracic Society …
Task Force, supported by the European Respiratory Society and American Thoracic Society …
[HTML][HTML] Oral glucocorticoid-sparing effect of mepolizumab in eosinophilic asthma
EH Bel, SE Wenzel, PJ Thompson… - New England journal …, 2014 - Mass Medical Soc
Background Many patients with severe asthma require regular treatment with oral
glucocorticoids despite the use of high-dose inhaled therapy. However, the regular use of …
glucocorticoids despite the use of high-dose inhaled therapy. However, the regular use of …
Clinical control and histopathologic outcome of asthma when using airway hyperresponsiveness as an additional guide to long-term treatment
JK Sont, LNA Willems, EH Bel… - American journal of …, 1999 - atsjournals.org
According to international guidelines, the level and adjustment of antiinflammatory treatment
for asthma are based solely on symptoms and lung function. We investigated whether a …
for asthma are based solely on symptoms and lung function. We investigated whether a …
The prevalence of severe refractory asthma
PPW Hekking, RR Wener, M Amelink… - Journal of Allergy and …, 2015 - Elsevier
Background Severe asthma is characterized by difficulty to achieve disease control despite
high-intensity treatment. However, prevalence figures of severe asthma are lacking …
high-intensity treatment. However, prevalence figures of severe asthma are lacking …
Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort
DE Shaw, AR Sousa, SJ Fowler… - European …, 2015 - Eur Respiratory Soc
U-BIOPRED is a European Union consortium of 20 academic institutions, 11 pharmaceutical
companies and six patient organisations with the objective of improving the understanding …
companies and six patient organisations with the objective of improving the understanding …
[HTML][HTML] Long-Term Effects of a Long-Acting β2-Adrenoceptor Agonist, Salmeterol, on Airway Hyperresponsiveness in Patients with Mild Asthma
D Cheung, MC Timmers, AH Zwinderman… - … England Journal of …, 1992 - Mass Medical Soc
Background. Asthma is characterized by hyperresponsiveness of the airways to
bronchoconstrictive stimuli. Long-acting β2-adrenoceptor agonists have been introduced as …
bronchoconstrictive stimuli. Long-acting β2-adrenoceptor agonists have been introduced as …
External validation of blood eosinophils, FENO and serum periostin as surrogates for sputum eosinophils in asthma
AH Wagener, SB de Nijs, R Lutter, AR Sousa… - Thorax, 2015 - thorax.bmj.com
Background Monitoring sputum eosinophils in asthma predicts exacerbations and improves
management of asthma. Thus far, blood eosinophils and FENO show contradictory results in …
management of asthma. Thus far, blood eosinophils and FENO show contradictory results in …