A role for 11C-methionine PET imaging in ACTH-dependent Cushing's syndrome

O Koulouri, A Steuwe, D Gillett, AC Hoole… - European Journal of …, 2015 - academic.oup.com
Objective We report our experience of functional imaging with 11C-methionine positron
emission tomography–computed tomography (PET–CT) co-registered with 3D gradient echo …

Modern imaging of pituitary adenomas

WA Bashari, R Senanayake… - Best practice & research …, 2019 - Elsevier
Decision-making in pituitary disease is critically dependent on high quality imaging of the
sella and parasellar region. Magnetic resonance imaging (MRI) is the investigation of choice …

New types of localization methods for adrenocorticotropic hormone-dependent Cushing's syndrome

R Senanayake, D Gillett, J MacFarlane… - Best Practice & …, 2021 - Elsevier
The management of endogenous Cushing's syndrome (CS) typically involves two key
steps:(i) confirmation of autonomous hypercortisolism and (ii) localization of the cause to …

[HTML][HTML] [11C]metomidate PET-CT versus adrenal vein sampling for diagnosing surgically curable primary aldosteronism: a prospective, within-patient trial

X Wu, R Senanayake, E Goodchild, WA Bashari… - Nature Medicine, 2023 - nature.com
Primary aldosteronism (PA) due to a unilateral aldosterone-producing adenoma is a
common cause of hypertension. This can be cured, or greatly improved, by adrenal surgery …

Successful treatment of residual pituitary adenoma in persistent acromegaly following localisation by 11C-methionine PET co-registered with MRI

O Koulouri, N Kandasamy, AC Hoole… - European Journal of …, 2016 - academic.oup.com
Objective To determine if functional imaging using 11C-methionine positron emission
tomography co-registered with 3D gradient echo MRI (Met-PET/MRI), can identify sites of …

Advances in the imaging of pituitary tumors

J MacFarlane, WA Bashari… - Endocrinology and …, 2020 - endo.theclinics.com
Pituitary adenomas (PA) are typically benign, slow-growing tumors of the adenohypophysis,
which come to attention because of associated endocrine dysfunction (eg …

In vivo imaging reveals increased eosinophil uptake in the lungs of obese asthmatic patients

N Farahi, C Loutsios, N Tregay, AKA Wright… - Journal of Allergy and …, 2018 - jacionline.org
To measure the time-dependent uptake of radiolabeled eosinophils from the blood into the
lungs (''pulmonary uptake''), serial images were acquired using SPECT/CT (Fig 1, H) and …

The SaeRS two-component system is a direct and dominant transcriptional activator of toxic shock syndrome toxin 1 in Staphylococcus aureus

ML Baroja, CA Herfst, KJ Kasper, SX Xu… - Journal of …, 2016 - Am Soc Microbiol
Toxic shock syndrome toxin 1 (TSST-1) is a Staphylococcus aureus superantigen that has
been implicated in both menstrual and nonmenstrual toxic shock syndrome (TSS). Despite …

PET-guided repeat transsphenoidal surgery for previously deemed unresectable lateral disease in acromegaly

WA Bashari, R Senanayake, O Koulouri, D Gillett… - Neurosurgical …, 2020 - thejns.org
OBJECTIVE The object of this study was to determine if revision transsphenoidal surgery
(TSS), guided by 11 C-methionine PET/CT coregistered with volumetric MRI (Met-PET/MR …

Use of autologous 99mTechnetium-labelled neutrophils to quantify lung neutrophil clearance in COPD

N Tregay, M Begg, A Cahn, N Farahi, K Povey… - Thorax, 2019 - thorax.bmj.com
Rationale There is a need to develop imaging protocols which assess neutrophilic
inflammation in the lung. Aim To quantify whole lung neutrophil accumulation in (1) healthy …