Patients with cystic fibrosis (CF) have low bone mineral density (BMD). The clinical
relevance of this is not clearly established. The aim of this study was to determine the …

The rate of endogenous cholecalciferol synthesis depends on the availability of biologically
effective ultraviolet light in solar and sky radiation. There is a striking seasonal variation in …

Patients with severe thalassaemia major suffer endocrine and other abnormalities before
their eventual death from iron overload due to repeated blood transfusions. The endocrine …

OBJECTIVE The importance of growth hormone (GH) for normal skeletal growth in
childhood and adolescence is well established but much less is known about its action on …

Seven patients with functioning renal transplants were found to have serum-inorganic-
phosphate levels below normal, and five of them had X-ray evidence of osteomalacia …

OBJECTIVE Short‐term GH replacement in hypopituitary adults increases bone turnover;
data on the consequences of longer‐term GH treatment are limited. We report on the effects …

We have evaluated two commercial assays for serum bone specific alkaline phosphatase
(bALP) as a marker of bone turnover in a group of 35 postmenopausal women with …

1. A competitive protein-binding assay for 25-hydroxy vitamin D (25-OHD) in saliva has been
established by adaptation of that previously described for 25-OHD in serum (Fairney et al …

This study has shown that it is possible to measure vitamin D metabolites and vitamin D
binding protein (DBP) in synovial fluid as well as serum. Significant amounts of 25-OHD, 24 …

We have evaluated three commercial assays for collagen cross-links, two urine assays and
a recently developed serum assay, as markers of bone turnover in 30 postmenopausal …