Apoptosis: getting rid of the bodies

Curr Biol. 1998 Sep 24;8(19):R693-5. doi: 10.1016/s0960-9822(98)70438-5.

Abstract

Cells that die by apoptosis need to be removed before lysis to preserve tissue integrity and function. Recent studies have identified components of the uptake machinery used by phagocytes, but much remains to be learnt, particularly about the recognition mechanisms and their coupling to the uptake machinery.

Publication types

  • Review

MeSH terms

  • ATP-Binding Cassette Transporters / genetics
  • ATP-Binding Cassette Transporters / physiology
  • Animals
  • Apoptosis Regulatory Proteins
  • Apoptosis*
  • Caenorhabditis elegans / cytology
  • Caenorhabditis elegans / genetics
  • Caenorhabditis elegans / physiology
  • Caenorhabditis elegans Proteins*
  • Drosophila melanogaster / cytology
  • Drosophila melanogaster / physiology
  • Helminth Proteins / genetics
  • Helminth Proteins / physiology
  • Humans
  • Insect Proteins / physiology
  • Mammals / physiology
  • Membrane Lipids / physiology
  • Membrane Proteins / genetics
  • Membrane Proteins / physiology
  • Phagocytosis / genetics
  • Phagocytosis / physiology*
  • Phosphatidylserines / physiology
  • Phosphoproteins / genetics
  • Phosphoproteins / physiology
  • Species Specificity
  • Surface Properties

Substances

  • ATP-Binding Cassette Transporters
  • Apoptosis Regulatory Proteins
  • CED-5 protein, C elegans
  • CED-6 protein, C elegans
  • CED-7 protein, C elegans
  • Caenorhabditis elegans Proteins
  • Helminth Proteins
  • Insect Proteins
  • Membrane Lipids
  • Membrane Proteins
  • Phosphatidylserines
  • Phosphoproteins