Is infant immunization a risk factor for childhood asthma or allergy?

Epidemiology. 1997 Nov;8(6):678-80. doi: 10.1097/00001648-199710000-00011.

Abstract

The Christchurch Health and Development Study comprises 1,265 children born in 1977. The 23 children who received no diphtheria/pertussis/tetanus (DPT) and polio immunizations had no recorded asthma episodes or consultations for asthma or other allergic illness before age 10 years; in the immunized children, 23.1% had asthma episodes, 22.5% asthma consultations, and 30.0% consultations for other allergic illness. Similar differences were observed at ages 5 and 16 years. These findings do not appear to be due to differential use of health services (although this possibility cannot be excluded) or con-founding by ethnicity, socioeconomic status, parental atopy, or parental smoking.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Asthma / epidemiology*
  • Asthma / immunology
  • Child
  • Child, Preschool
  • Confidence Intervals
  • Confounding Factors, Epidemiologic
  • Cross-Sectional Studies
  • Eczema / epidemiology
  • Female
  • Humans
  • Hypersensitivity / epidemiology*
  • Hypersensitivity / immunology
  • Infant
  • Infant, Newborn
  • Longitudinal Studies
  • Male
  • New Zealand / epidemiology
  • Odds Ratio
  • Retrospective Studies
  • Risk Factors
  • Vaccination / adverse effects*
  • Virus Diseases / epidemiology
  • Virus Diseases / immunology
  • Virus Diseases / prevention & control