Peripheral nervous system involvement in a large cohort of human immunodeficiency virus-infected individuals

Arch Neurol. 1993 Feb;50(2):167-71. doi: 10.1001/archneur.1993.00540020045016.

Abstract

Objective: In individuals who were infected with the human immunodeficiency virus (HIV) we determined the prevalence of peripheral neuropathies (PNs) and explored the relationship between immunologic competence and nerve function.

Design: Cohort survey.

Setting: US Air Force medical center.

Patients: Population based. Seven hundred ninety-eight of 817 HIV-positive personnel identified by US Air Force HIV screening program from 1985 to 1989. Average age of cohort was 29.2 years. The majority were male with early-stage HIV disease.

Main outcome measures: Neurologists examined all subjects for symptoms and signs of PN. We grouped patients by CD4 T-lymphocyte count. We further studied 300 HIV-infected volunteers without clinical evidene of PN by nervex

Publication types

  • Comparative Study

MeSH terms

  • Acquired Immunodeficiency Syndrome / complications*
  • Acquired Immunodeficiency Syndrome / immunology
  • Acquired Immunodeficiency Syndrome / physiopathology
  • CD4 Antigens / analysis
  • Cell Count
  • Cohort Studies
  • Female
  • Humans
  • Male
  • Neural Conduction
  • Peripheral Nerves / physiopathology
  • Peripheral Nervous System Diseases / diagnosis
  • Peripheral Nervous System Diseases / etiology*
  • T-Lymphocytes / immunology

Substances

  • CD4 Antigens