Drug-induced pulmonary disease. Part 2: Noncytotoxic drugs

Am Rev Respir Dis. 1986 Mar;133(3):488-505. doi: 10.1164/arrd.1986.133.3.488.

Abstract

Nonchemotherapeutic drugs may also cause pulmonary parenchymal alterations. Mechanisms of pulmonary damage by these agents are diverse and may involve alterations of pulmonary homeostasis. Clinical features of noncytotoxic, drug-induced pulmonary disease are more heterogeneous than those associated with cytotoxic drugs, and several clinical syndromes are equally represented. Treatment and outcome vary with each individual drug and clinical presentation. In part 2, clinical and pathogenic aspects of noncytotoxic, drug-induced pulmonary disease are discussed.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Anti-Arrhythmia Agents / adverse effects
  • Anti-Arrhythmia Agents / pharmacology
  • Anti-Bacterial Agents / adverse effects
  • Anti-Bacterial Agents / pharmacology
  • Anti-Inflammatory Agents / adverse effects
  • Anti-Inflammatory Agents / pharmacology
  • Antipsychotic Agents / adverse effects
  • Antipsychotic Agents / pharmacology
  • Central Nervous System / drug effects
  • Central Nervous System / physiopathology
  • Disease Susceptibility
  • Diuretics / adverse effects
  • Diuretics / pharmacology
  • Drug Hypersensitivity / etiology
  • Drug-Related Side Effects and Adverse Reactions*
  • Extracellular Matrix / drug effects
  • Homeostasis / drug effects
  • Humans
  • Kidney Diseases / chemically induced
  • Lung / diagnostic imaging
  • Lung / drug effects
  • Lung / pathology
  • Lung Diseases / chemically induced*
  • Lung Diseases / diagnostic imaging
  • Lung Diseases / pathology
  • Lung Diseases / therapy
  • Narcotics / adverse effects
  • Narcotics / pharmacology
  • Oxidation-Reduction
  • Peptide Hydrolases / metabolism
  • Protease Inhibitors / metabolism
  • Pulmonary Edema / chemically induced
  • Pulmonary Edema / physiopathology
  • Radiography
  • Respiratory Hypersensitivity / chemically induced
  • Risk
  • Sympathomimetics / adverse effects
  • Sympathomimetics / pharmacology

Substances

  • Anti-Arrhythmia Agents
  • Anti-Bacterial Agents
  • Anti-Inflammatory Agents
  • Antipsychotic Agents
  • Diuretics
  • Narcotics
  • Protease Inhibitors
  • Sympathomimetics
  • Peptide Hydrolases