Mega-trials for blockbusters

JAMA. 2013 Jan 16;309(3):239-40. doi: 10.1001/jama.2012.168095.
No abstract available

MeSH terms

  • Costs and Cost Analysis
  • Drug Industry / economics
  • Drug Therapy
  • Endpoint Determination*
  • Humans
  • Mortality
  • Multicenter Studies as Topic
  • Patient Selection
  • Randomized Controlled Trials as Topic / economics*
  • Randomized Controlled Trials as Topic / statistics & numerical data
  • Research Design*
  • Research Support as Topic
  • Sample Size
  • Treatment Outcome