Abstract
The in vivo composition of the mycelial extracellular matrix (ECM) of Aspergillus fumigatus during host invasion is reported here for the first time. A new galactosaminogalactan and the galactomannan were the major polysaccharides of the in vivo ECM. The composition of the ECM in vivo varied with the aspergillosis pathologies.
MeSH terms
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Animals
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Aspergillus fumigatus / growth & development
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Aspergillus fumigatus / metabolism
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Aspergillus fumigatus / physiology*
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Biofilms / growth & development*
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Extracellular Matrix / chemistry*
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Galactose / analogs & derivatives
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Humans
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Mannans / analysis
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Mice
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Polysaccharides / analysis
Substances
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Mannans
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Polysaccharides
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galactosaminogalactan
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galactomannan
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Galactose