Abstract
Interleukin-7 (IL-7) is required for the development and survival of T cells and plays a critical role in modulating T-cell homeostasis. This review will address current understanding of IL-7 biology, review recent clinical experiences and discuss potential future clinical applications of IL-7, or IL-7 blockade, in the setting of disease.
Publication types
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Research Support, N.I.H., Intramural
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Review
MeSH terms
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Autoimmune Diseases / immunology
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Autoimmune Diseases / therapy
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HIV Infections / immunology
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HIV Infections / therapy
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Homeostasis / immunology
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Humans
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Immunotherapy / methods*
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Interleukin-7 / immunology*
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Neoplasms / immunology
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Neoplasms / therapy
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Randomized Controlled Trials as Topic
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T-Lymphocytes / immunology*