Appearance of bronchioloalveolar carcinoma and the rapid progression into invasive papillary adenocarcinoma

Gen Thorac Cardiovasc Surg. 2009 Apr;57(4):224-7. doi: 10.1007/s11748-008-0345-5. Epub 2009 Apr 15.

Abstract

The prognostic importance of bronchioloalveolar carcinoma in comparison to the invasive subtypes needs to be studied, although the natural history of a pure bronchioloalveolar carcinoma is still unclear. We report the appearance of a pure ground-glass opacity that demonstrates rapid progression into a solid component in the central area, pathologically revealing a minimally invasive papillary adenocarcinoma. Considering the findings of previous reports, as well as our case, we need to pay careful attention to the follow-up of a patient who has even a pure ground-glass opacity when the patient had a history of an invasive lung cancer. We need also to perform curative surgery with optimal timing.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / pathology*
  • Adenocarcinoma / surgery
  • Adenocarcinoma, Bronchiolo-Alveolar / pathology*
  • Adenocarcinoma, Bronchiolo-Alveolar / surgery
  • Aged
  • Carcinoma, Papillary / pathology*
  • Carcinoma, Papillary / surgery
  • Disease Progression
  • Humans
  • Lung Neoplasms / pathology*
  • Lung Neoplasms / surgery
  • Male
  • Neoplasm Invasiveness
  • Neoplasms, Second Primary / pathology*
  • Neoplasms, Second Primary / surgery