Abstract
Recently published reports suggest that the combination of aminoglycosides with ceftazidime may increase the risk of renal disease in cystic fibrosis. We describe a case of unusually severe acute tubular necrosis occurring in an adolescent with cystic fibrosis receiving i.v. gentamicin plus ceftazidime and discuss the possible mechanisms.
MeSH terms
-
Adolescent
-
Aminoglycosides / adverse effects
-
Anti-Bacterial Agents / administration & dosage
-
Anti-Bacterial Agents / adverse effects*
-
Bacterial Infections / complications
-
Bacterial Infections / drug therapy*
-
Cystic Fibrosis / complications*
-
Drug Combinations
-
Female
-
Humans
-
New South Wales
-
Renal Dialysis
-
Renal Insufficiency / chemically induced*
-
Renal Insufficiency / therapy
Substances
-
Aminoglycosides
-
Anti-Bacterial Agents
-
Drug Combinations