Abstract
Excess collagen deposition occurs in pulmonary fibrosis. A new study suggests that collagen overproduction may originate from cells derived from bone marrow precursors rather than parenchymal lung fibroblasts.
MeSH terms
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Animals
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Bleomycin / pharmacology
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Bone Marrow Cells / pathology*
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Cell Lineage
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Collagen / metabolism
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Fibroblasts / metabolism
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Fibrosis / pathology*
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Hematopoietic Stem Cells / cytology
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Humans
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Lung / pathology*
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Models, Biological
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Pulmonary Fibrosis / pathology*
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Stem Cells / metabolism