Abstract
Recent studies demonstrate the capacity of BM-derived cells to engraft as differentiated cells of a variety of organs, including lung. In this paper, we review the current state-of-the-art in this area. We also summarize our work demonstrating that cultured adherent marrow cells can serve as progenitors of lung alveolar epithelium.
MeSH terms
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Animals
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Aquaporin 5
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Aquaporins / metabolism
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Biomarkers
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Bone Marrow Cells / cytology
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Bone Marrow Cells / physiology*
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Cell Adhesion / physiology*
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Cell Differentiation / physiology*
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Cell Size / physiology
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Cells, Cultured
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DNA-Binding Proteins / metabolism
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Hepatocyte Nuclear Factor 3-beta
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Lung / cytology
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Lung / embryology*
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Lung / physiology*
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Membrane Glycoproteins
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Membrane Proteins / metabolism
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Mice
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Nuclear Proteins / metabolism
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Proteins / metabolism
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Respiratory Mucosa / cytology
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Respiratory Mucosa / embryology*
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Respiratory Mucosa / physiology*
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Stem Cells / cytology
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Stem Cells / physiology*
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Thyroid Nuclear Factor 1
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Transcription Factors / metabolism
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Uteroglobin*
Substances
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Aqp5 protein, mouse
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Aquaporin 5
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Aquaporins
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Biomarkers
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DNA-Binding Proteins
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Foxa2 protein, mouse
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Gp38 protein, mouse
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Membrane Glycoproteins
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Membrane Proteins
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Nuclear Proteins
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Proteins
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Scgb1a1 protein, mouse
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Thyroid Nuclear Factor 1
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Transcription Factors
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Hepatocyte Nuclear Factor 3-beta
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Uteroglobin