Abstract
KL-6 is a mucinous glycoprotein that is preferentially expressed by alveolar type 2 cells. Plasma KL-6 was higher in infants with chronic lung disease (n = 12) than in infants without chronic lung disease (n = 14) on day 0-1, 10, and 30 (P =.04). KL-6 correlated with the alveolar-arterial oxygen tension difference on day 10 and day 30. Plasma KL-6 may be useful as an early marker of chronic lung disease and an indicator of severity.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antigens / blood*
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Antigens, Neoplasm
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Biomarkers
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Bronchopulmonary Dysplasia / diagnosis*
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Female
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Glycoproteins / blood*
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Humans
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Infant, Newborn
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Infant, Premature*
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Male
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Mucin-1
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Mucins / blood*
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Peptide Fragments*
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Procollagen*
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Retrospective Studies
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Severity of Illness Index
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Statistics, Nonparametric
Substances
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Antigens
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Antigens, Neoplasm
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Biomarkers
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Glycoproteins
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MUC1 protein, human
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Mucin-1
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Mucins
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Peptide Fragments
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Procollagen
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procollagen Type III-N-terminal peptide