Chest
Major Pulmonary Artery Stenosis Causing Pulmonary Hypertension in Sarcoidosis
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CASE REPORT
A 39-year-old woman was well until 1967 when she developed intermittent migratory chest pain. A chest roentgenogram revealed bilateral hilar and paratracheal adenopathy with normal pulmonary parenchyma. A scalene node biopsy specimen revealed noncaseating granulomas. In 1973, the patient was admitted to the University of Michigan with right 6th and 7th cranial nerve paresis. She had no pulmonary symptoms and was receiving no medication. Pulmonary function testing revealed only a mild reduction
COMMENTS
Stenosis of large pulmonary arteries has been previously demonstrated in patients with sarcoidosis,6, 7, 8, 9, 10 but stenoses sufficiently severe to result in pulmonary hypertension have not been well documented. Battesti and colleagues9 have reported a patient with sarcoidosis who had stenoses of central pulmonary arteries and clinical evidence of pulmonary hypertension, but pulmonary artery pressures were not measured and the relative contributions of central and peripheral vascular
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