Chest
Original ResearchImprovement in Quadriceps Strength and Dyspnea in Daily Tasks After 1 Month of Electrical Stimulation in Severely Deconditioned and Malnourished COPD
Section snippets
Subjects
The following procedures were performed in accordance with the standards of the Committee on Human Experimentation at our institution, which approved the study. The criteria for participation in the study were as follows: (1) experiencing severe bronchial obstruction (ie, COPD and/or bronchiectasis) but with no evidence of cardiovascular, renal, or hepatic diseases; (2) FEV1 ≤ 50% predicted with an FEV1/FVC ratio of < 70%; (3) disability and malnutrition as established by a BMI of < 22 kg/m2;
Patients Studied
As a whole group (n = 17), patients exhibited severe chronic bronchial obstruction (mean FEV1, 30 ± 3% predicted) and severe disability and malnutrition considering their very low mean BMI (18 ± 2.5 kg/m2) [Table 1]. Both groups showed a marked decrease in muscle strength (ES + UR group, 24 ± 18% predicted; UR group, 22 ± 11% predicted26), MM (ES + UR group 49 ± 14% predicted; UR group, 58 ± 8% predicted30), and 6 min-walking distance (ES + UR group, 42 ± 14% predicted; UR group, 39 ± 21%
Discussion
This study sought to evaluate whether ES was a useful additive strategy to UR (ie, ALM) in severely deconditioned COPD patients with low BMIs who were unable to perform cycle ergometry. Our results showed that ES was feasible to perform and was well-tolerated by these patients. The main result of this study was that the combination of ES and UR enabled improvements in quadriceps muscle strength and dyspnea in the performance of daily tasks to a greater extent than UR alone.
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Reproduction of this article is prohibited without written permission from the American College of Chest Physicians (www.chestjournal.org/misc/reprints.shtml)
This research was supported by grants from the Association pour le Traitement, la Rééducation et la Réadaptation des Insuffisants Respiratoires (ATRIR), “Bourse André Dion,” Nyons, France.