Chest
Original Research: ASTHMAOutcomes of a Web-Based Patient Education Program for Asthmatic Children and Adolescents
Section snippets
Study Design
The current investigation was a nonrandomized, nonstratified, multicenter, real-life study comprising two intervention groups and one control group (Fig 1). The investigation was conducted between July 2001 and December 2002 in 36 study centers nationwide, including general practitioner (GP) and specialist offices as well as asthma outpatient facilities of hospitals.
Intervention Groups
All eligible patients were invited to join a standardized patient management program (SPMP). They had the option to self select
Results
The original study sample consisted of 358 patients. A further 80 patients were interested in participating but could not be included as they did not meet inclusion criteria. Complete medical resource use data at all follow-up visits were available for 178 patients (49.7%) who were defined as PPP (Table 2). Medical resource use data of 56 study completers were insufficient for analysis (15.6%).
Reasons for study discontinuation (n = 124; 34.6%) were as follows: relocation of patients (n = 6),
Discussion
The positive impact of the SPMP is fortified by the additional IEP as demonstrated in several outcome measures, including morbidity costs savings, QoL, absenteeism from school, number of asthma-related emergencies, and use of short-acting β-agonists. Our subgroup analysis demonstrates that, within 1 year, morbidity cost savings exceed the intervention costs in patients who belong to risk groups (benefit-cost ratio > 1). Similar findings that reflect the influence of target population
Appendix
The supporters and active study investigators in the following institutions participated in this study: CJD Berchtesgaden, Klinik Schönsicht, Klinik Santa Maria, Marien-Hospital Wesel, Kinderklinik Gilead, Prinzregent Luitpold Kinderklinik, Praxis Dr. Laub, Institut für Verhaltensmedizin IAV, Praxis Dr. Straub/Dr. Köhler, Praxis Dr. Blum/Dr. Butsch v.d. Heydt, Praxis Dr. Averbeck, Praxis Dr. Bolz, Kinderklinik des Klinikums Nürnberg-Süd, Praxis Dr. Bulle, Praxis Dr. Maier, Fachkliniken Wangen,
ACKNOWLEDGMENT
The authors thank all patients and their relatives for their cooperation in this study.
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GlaxoSmithKline Germany has cofinanced the development of the IEP. GlaxoSmithKline has also financed the entire study including an investigator bonus of 25 Euros for every complete control group patient documentation. Furthermore, GlaxoSmith-Kline has arranged three investigators meetings between 2001 and 2003. Travel expenses were refunded at the initial meeting. The IEP was designed by the enterprise Forum Telemedizin GmbH, which is owned and headed by Dr. Horn, who provided private funds in addition to the financial support granted by GlaxoSmithKline.
Dr. Lecheler has not received any honoraria from GlaxoSmith-Kline in this investigation, but in some cases travel expenses were refunded by GlaxoSmithKline.
Representing an institution that owns the intellectual property rights of a traditional patient education program, Dr. Lecheler has advised Dr. Horn in designing the Internet education tool. In the past, Dr. Lecheler was a paid consultant/speaker in several projects with GlaxoSmithKline involvement. Professor Schaefer was the doctoral thesis advisor of the first author, Dr. Runge, whose thesis deals with the IEP. In the past, Professor Schaefer has raised third-party funds from different pharmaceutical companies.
Drs. Runge and Tews are employees of GlaxoSmithKline.
Reproduction of this article is prohibited without written permission from the American College of Chest Physicians (www.chestjournal.org/misc/reprints.shtml).