Chest
Clinical InvestigationsThoracoscopic Lung Biopsy Is a Safe Procedure in Diagnosing Usual Interstitial Pneumonia
Section snippets
Patients and Handling of Specimens
Histopathologically typical cases of UIP were collected from the files of the Department of Pathology, Oulu University Hospital, Oulu, Finland. Biopsies between January 1973 and December 2002 were reevaluated for UIP histopathology (R.K.W., P.P.). Open-lung biopsies were performed from January 1973 to December 1992; after that time, a thoracoscopic technique was mainly used. Altogether, 76 patients (34 women and 42 men) presenting with UIP were included. Lung biopsies were performed under
Clinical Findings and Symptoms
The study population consisted of 42 men (55.3%) and 34 women (44.7%), with a mean age at the time of biopsy of 56.7 years (range, 21 to 77 years). The mean age of the women was 54.7 years (range, 21 to 74 years), and the mean age of the men was 58.3 years (range, 34 to 77 years). A total of 42 patients (55.3%) underwent open-lung biopsy, and 34 patients (44.7%) underwent thoracoscopic procedures. There were 17 current (22.4%) and 23 former smokers (30.3%) with an average smoking history of
Discussion
The short-term postoperative mortality (< 30 days) in our study was 5.3%, which was considerably lower than that in another study8 of UIP (21.7%), considering the idiopathic type of the disease. In the present study, all four patients who died within 1 month after the operation had undergone open thoracotomy. In patients who underwent thoracoscopy, the preoperative and postoperative mortalities were nonexistent, and also the morbidity was low. Therefore, the thoracoscopic operation can be
Acknowledgment
We thank Dr. Risto Pokela and Dr. Martti Mosorin for their comments on thoracic surgery and VATS. We also thank Mr. Manu Tuovinen and Ms. Päivi Koukkula for technical assistance.
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Supported by The Finnish Anti-Tuberculosis Association Foundation, Juselius Foundation, Maud Kuistila Foundation and Fundings from Oulu and Helsinki University Hospitals.
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