Chest
Clinical InvestigationsSleepObstructive Sleep Apnea in Infants and Its Management With Nasal Continuous Positive Airway Pressure
Section snippets
Materials and Methods
Studies were performed on 24 infants (15 boys and 9 girls from 1 to 51 weeks old), who had been referred to the sleep disorders clinic for investigation of OSA (Table 1). The infants were selected for CPAP treatment because they had mixed and obstructive apneas of > 5 apneas/h of sleep that were recorded during an overnight polysomnographic study (in 21 infants) or an overnight ambulatory study (in 3 infants). The mean (± SEM) gestation age was 37.6 ± 0.7 weeks old (range, 30 to 42 weeks old);
Effects of nCPAP on Sleep Apnea and Sleep
All infants had obstructive and central events recorded on their diagnostic study that were associated with decreases in Sao2 (Fig 1). Sixteen of the 24 infants had a CPAP PD study the night after their diagnostic study. The remaining infants were treated with low-level nCPAP (3.7 cm H2O) during sleep as inpatients of the hospital, until their CPAP PD study could be performed. In total, 21 of the infants underwent a CPAP PD study within 2 weeks of their diagnostic study. Of these 21 infants, 18
Discussion
We successfully used nCPAP via mask to treat OSA in > 85% of infants, and it was possible to use CPAP as a long-term treatment in the infants’ homes. The previous use of nCPAP to treat OSA in infants has been limited. CPAP delivered via nasal prongs or an endotracheal tube has been used extensively to treat respiratory distress and apnea of prematurity in preterm infants.15 This application of CPAP was applied to support and inflate the lungs, rather than to support the upper airway. There have
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Supported by the National Health and Medical Research Council (NHMRC)of Australia.