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Clinical Investigations in Critical CareOutcome of Intensive Care in Patients With HIV Infection
Section snippets
METHODS
This study includes patients admitted to the Medical ICU of Beth Israel Hospital, New York City between November 1, 1991, and October 31, 1992. Beth Israel is a 960-bed acute care hospital and a designated AIDS treatment center. It has an outpatient AIDS clinic and a 12-bed AIDS inpatient unit. Patients were enrolled in this study during their admission to the ICU if they had proven HIV infection or had an AIDS-defining opportunistic infection.16, 20 Decisions on who is admitted to the ICU are
RESULTS
During the 1-year study period, there were 1,550 hospital admissions for HIV-infected patients, and 199 patients (13%) had PCP. In this period, 65 (4.2%) patients were admitted to the ICU and enrolled in this study.
The characteristics of the patients admitted to the ICU are shown in Table 1. They included 44 men and 21 women, and their mean age was 39.3 years. Black and Hispanic patients accounted for 75% of the study population. Injection drug users represented the largest transmission
DISCUSSION
The literature on intensive care of patients with AIDS emphasizes respiratory failure due to PCP as the major cause of admission.1 Data collected between 1980 and 1987 describe a dismal outcome for patients with AIDS, PCP, and respiratory failure who require intubation and mechanical ventilation. The National Institutes of Health Workshop on pulmonary complications of AIDS reported on data collected from six centers.3 Eighty-eight of 102 patients (86%) who required mechanical ventilation died
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Cited by (85)
What determines do-not-resuscitate status in critically ill HIV-infected patients admitted to ICU?
2019, Journal of Critical CareCharacteristics and outcomes of HIV-1-infected patients with acute respiratory distress syndrome
2015, Journal of Critical CareCitation Excerpt :HIV-1–infected subjects were also more likely to have prior bouts of sepsis and hospital-acquired infections. As shown in other studies, the most common cause of ARDS in this cohort was severe pneumonia [1,6,18]. HIV-1–infected subjects had significantly higher APACHE II scores due to their lower serum albumin levels, sodium levels, and white blood counts, consistent with previous studies [19].
Revision accepted May 26.
Reprint requests: Dr. Rosen, Division of Pulmonary and Critical Care Medicine, Beth Israel Medical Center, 1st Avenue and 16th Street, New York, NY 10003