Asthma, Rhinitis, Other Respiratory DiseasesResponses to bronchial challenge submitted for approval to use inhaled β2-agonists before an event at the 2002 winter olympics☆,☆☆
Section snippets
Methods
References were provided for methodologies to perform the various bronchial provocation tests.18, 19, 21, 22, 23, 26, 28, 29 The actual measurements of FEV1 before and after challenge and after bronchodilator use had to be provided to the panel with the source of the predicted values used.
Comparisons between the groups who had positive and negative results to each test were made by using the F test or the variance ratio test.30
Results
There were 2517 athletes at Salt Lake City, and of these, 36.3% were women. There were 165 individual applications for use of IBAs (6.6% of all participants), and these included 105 men and 60 (36.7%) women. Of these 165, 147 (89%) athletes submitted sufficient data to permit inclusion in the analysis of challenge tests. Some athletes submitted more than one result (ie, the results of methacholine and exercise or the results of methacholine and bronchodilator challenge), and in all, 163 tests
Discussion
The majority (89%) of applicants were able to meet the requirements of performing or providing test results for a bronchial challenge with 3 months' notice.
Although the response to a bronchodilator would normally be the simplest challenge to confirm the AHR of asthma, only 17% of the applicants submitted an acute response to a bronchodilator. No athlete was unfairly excluded from using IBAs because the value of 12% or more of predicted FEV1 was used for a positive bronchodilator test result
Acknowledgements
We thank Dr Patrick Schamasch of the IOC-MC for his help and guidance during the course of this project.
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Cited by (0)
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Supported by the Medical Commission of the International Olympic Committee.
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Reprint requests: Sandra Anderson, PhD, DSc, Department of Respiratory Medicine, E11S, Royal Prince Alfred Hospital, Camperdown NSW 2050, Australia.