MINI-SYMPOSIUM: RESPIRATORY SYNCYTIAL VIRUSLong-term consequences of respiratory syncytial virus (RSV) bronchiolitis
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Cited by (48)
Nanobodies® as inhaled biotherapeutics for lung diseases
2017, Pharmacology and TherapeuticsEthical considerations and rationale of the MAKI trial: A multicenter double-blind randomized placebo-controlled trial into the preventive effect of palivizumab on recurrent wheezing associated with respiratory syncytial virus infection in children with a gestational age of 33-35weeks
2012, Contemporary Clinical TrialsCitation Excerpt :Of these hospitalised children, about 10% of infants required mechanical ventilation at a Paediatric Intensive Care Unit [3–5]. After the acute illness, approximately 50% of children with RSV bronchiolitis will develop recurrent episodes of wheeze up to school age, associated with reduced health-related quality of life over a broad range of domains, including lung, gastrointestinal tract and sleeping domain [6,7]. Although the burden of disease is considerable, RSV-associated mortality in healthy term infants is probably low, published estimates vary between 0 and 8% [8–11].
Cost-effectiveness of potential infant vaccination against respiratory syncytial virus infection in The Netherlands
2012, VaccineCitation Excerpt :Risk factors for RSV-hospitalization include prematurity, congenital heart disease (CHD) and bronchopulmonary dysplasia (BPD). RSV-induced bronchiolitis is associated with severe episodes of recurrent wheezing in infancy and asthma in 8–70% of cases [11–13]. In school-aged children, wheeze is no longer associated with a history of RSV-hospitalization [11,12].
The Management of Pre-School Wheeze
2011, Paediatric Respiratory ReviewsSerious Early Childhood Wheezing After Respiratory Syncytial Virus Lower Respiratory Tract Illness in Preterm Infants
2010, Clinical TherapeuticsCitation Excerpt :However, limited studies have focused on the incidence of early childhood wheezing in premature infants infected with RSV.14,15 The reported prevalence and duration of the wheezing vary widely; epidemiologic studies have reported that wheezing after RSV-LRI occurs in 16% to 71% of patients.8,14,16-18 In their population-based birth cohort study, Henderson et al16 reported a cumulative prevalence of wheezing of 28.1% in the RSV group and 13.1% in the control group at 30 to 42 months.
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Corresponding author: Dr. J.L.L. Kimpen, University Medical Centre, 3508 AB Utrecht, The Netherlands. Tel: 0031 (0)302504194 Fax: 0031 (0)302505349 e-mail: [email protected]