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Diet and alcohol consumption and lung cancer risk in the New York State Cohort (United States)

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Abstract

The relationship between diet and alcohol and lung cancer was evaluated among participants of the New York State Cohort (United States),comprising 27,544 men (395 cases) and 20,456 women (130 cases) who completed a brief mailed questionnaire in 1980. Participants were followed up through1987 with the assistance of the New York State Department of Health's Vital Statistics Section and Cancer Registry. Among men, inverse relationships with vitamin C, folate, and carotenoids, and positive associations with total fat, monounsaturated and saturated fat were observed after adjusting for age, education, cigarettes/day, years smoking, and total energy intake. The relationships observed with folate and saturated fat were stronger for heavy smokers. Also, the effect of folate, total fat, and monounsaturated fat seemed to be limited to squamous cell carcinomas. We found no indication that cholesterol or polyunsaturated fat was associated with lung cancer. Diet did not appear to exert a major role on lung cancer risk among women. Although diet modification should never be considered a substitute for smoking cessation, its role as an additional strategy in lung cancer prevention deserves attention.

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References

  1. American Cancer Society. Cancer Facts and Figures-1996. New York, NY (USA): American Cancer Society, 1996.

    Google Scholar 

  2. Ziegler RG, Mayne ST, Swanson CA. Nutrition and lung cancer. Cancer Causes Control 1996; 7: 157–77.

    Article  PubMed  CAS  Google Scholar 

  3. Bandera EV, Freudenheim JL, Graham S, et al. Alcohol consumption and lung cancer in white males. Cancer Causes Control 1992; 3: 85–93.

    Article  Google Scholar 

  4. Potter JD, Sellers TA, Folsom AR, McGovern PG. Alcohol, beer, and lung cancer in postmenopausal women. The Iowa Women's Health Study. Ann Epidemiol 1992; 2: 587–95.

    Article  PubMed  CAS  Google Scholar 

  5. De Stefani E, Correa P, Fierro L, Fontham ETH, Chen V, Zavala D. The effect of alcohol on the risk of lung cancer in Uruguay. Cancer Epidemiol Biomark Prev 1993; 2: 21–6.

    CAS  Google Scholar 

  6. World Health Organization. International Classification of Diseases, Ninth Revision. Geneva, Switzerland: WHO, 1977.

    Google Scholar 

  7. US Department of Agriculture. Composition of Foods. Washington, DC: US GPO, 1963; USDA Handbook No. 7.

    Google Scholar 

  8. US Department of Agriculture. Composition of Foods. Washington, DC: US GPO, 1976-89; USDA Handbook No. 8, Revisions 8.1-8.17, 8.21.

    Google Scholar 

  9. US Department of Agriculture. Nutritive Value of American Foods in Common Units. Washington, DC: US GPO, 1975; USDA Handbook No. 456.

    Google Scholar 

  10. Paul A, Southgate D. McCance and Widdowson's The Composition of Foods. New York, NY (USA): Elsevier/ North-Holland Biomedical Press, 1978.

    Google Scholar 

  11. Pennington JAT. Dietary Nutrient Guide. Westport, CT (USA): Avi Publishing Company, 1976.

    Google Scholar 

  12. Pennington JAT. Bowes and Church's Food Values of Portions Commonly Used. Philadelphia, PA (USA): JB Lippincott Company, 1985.

    Google Scholar 

  13. Pennington JAT. Bowes and Church's Food Values of Portions Commonly Used. Philadelphia, PA (USA): JB Lippincott Company, 1989.

    Google Scholar 

  14. Willett W. Implications of total energy intake for epidemiologic analyses. In: Willett W. Nutritional Epidemiology. New York, NY (USA): Oxford University Press, 1990: 245–71.

    Google Scholar 

  15. Sies H, Stahl W. Vitamins E and C, ß-carotene, and other carotenoids as antioxidants. Am J Clin Nutr 1995; 62(Suppl): 1315s–21s

    PubMed  CAS  Google Scholar 

  16. Koo LC. Dietary habits and lung cancer risk among Chinese females in Hong Kong who never smoked. Nutr Cancer 1988; 11: 155–72.

    PubMed  CAS  Google Scholar 

  17. Fontham ETH, Pickle LW, Haenszel W, Correa P, Lin Y, Falk RT. Dietary vitamins A and C and lung cancer risk in Louisiana. Cancer 1988; 62: 2267–73.

    Article  PubMed  CAS  Google Scholar 

  18. Le Marchand L, Yoshizawa CN, Kolonel LN, Hankin JH, Goodman MT. Vegetable consumption and lung cancer risk: A population-based case-control study in Hawaii. JNCI 1989; 81: 1158–64.

    PubMed  CAS  Google Scholar 

  19. Candelora EC, Stockwell HG, Armstrong AW, Pinkham PA. Dietary intake and risk of lung cancer among women who never smoked. Nutr Cancer 1992; 17: 263–70.

    PubMed  CAS  Google Scholar 

  20. Kromhout D. Essential micronutrients in relation to carcinogenesis. Am J Clin Nutr 1987; 45: 1361–7.

    PubMed  CAS  Google Scholar 

  21. Knekt P, Järvinen R, Seppänen R, et al. Dietary antioxidants and the risk of lung cancer. Am J Epidemiol 1991; 134: 471–9.

    PubMed  CAS  Google Scholar 

  22. Hinds MW, Kolonel LN, Hankin JH, Lee J. Dietary vitamin A, carotene, vitamin C and risk of lung cancer in Hawaii. Am J Epidemiol 1984; 119: 227–37.

    PubMed  CAS  Google Scholar 

  23. Kalandidi A, Katsouyanni K, Voropoulou N, Bastas G, Saracci R, Trichopoulos D. Passive smoking and diet in the etiology of lung cancer among non-smokers. Cancer Causes Control 1990; 1: 15–21.

    Article  PubMed  CAS  Google Scholar 

  24. Chow WH, Schuman LM, McLaughlin JK, et al. A cohort study of tobacco use, diet, occupation, and lung cancer mortality. Cancer Causes Control 1992; 3: 247–54.

    Article  PubMed  CAS  Google Scholar 

  25. Byers TE, Graham S, Haughey BP, Marshall JR, Swanson MK. Diet and lung cancer risk: Findings from the Western New York Diet Study. Am J Epidemiol 1987; 125: 351–63.

    PubMed  CAS  Google Scholar 

  26. Jain M, Burch JD, Howe GR, Risch HA, Miller AB. Dietary factors and risk of lung cancer: Results from a case-control study, Toronto, 1981-1985. Int J Cancer 1990; 45: 287–93.

    PubMed  CAS  Google Scholar 

  27. Shekelle RB, Lepper M, Liu S, Maliza C, Raynor WJ, Rossof AH. Dietary vitamin A and risk of cancer in the Western Electric Study. Lancet 1981; 2: 1185–90.

    Article  PubMed  CAS  Google Scholar 

  28. Ziegler RG, Mason TJ, Stemhagen A, et al. Dietary carotene and vitamin A and risk of lung cancer among white men in New Jersey. JNCI 1984; 73: 1429–35.

    PubMed  CAS  Google Scholar 

  29. Ziegler RG, Mason TJ, Stemhagen A, et al. Carotenoid intake, vegetables, and the risk of lung cancer among white men in New Jersey. Am J Epidemiol 1986; 123: 1080–93.

    PubMed  CAS  Google Scholar 

  30. Wu AH, Henderson BE, Pike MC, Yu MC. Smoking and other risk factors for lung cancer in women. JNCI 1985; 74: 747–51.

    PubMed  CAS  Google Scholar 

  31. Mayne ST, Janerich DT, Greenwald P, et al. Dietary beta-carotene and lung cancer risk in U.S. never smokers. JNCI 1994; 86: 33–8.

    PubMed  CAS  Google Scholar 

  32. The Alpha-Tocopherol, Beta Carotene Cancer Prevention Study Group. The effect of vitamin E and beta-carotene on the incidence of lung cancer and other cancers in male smokers. N Engl J Med 1994; 330: 1029–35.

    Article  Google Scholar 

  33. Albanes D, Heinonen O, Huttunen JK, et al. Effects of α-tocopherol and β-carotene supplements on cancer incidence in the Alpha-Tocopherol Beta-Carotene Cancer Prevention Study. Am J Clin Nutr 1995; 62(Suppl): 1427s–30s.

    PubMed  CAS  Google Scholar 

  34. Byers T, Guerrero N. Epidemiologic evidence for vitamin C and vitamin E in cancer prevention. Am J Clin Nutr 1995; 626(Suppl): 1385S–92S.

    PubMed  CAS  Google Scholar 

  35. Bandera EV, Graham S, Freudenheim JL, et al. Folate and alcohol consumption and the risk of lung cancer [Abstract]. FASEB J 1991; 5: A562.

    Google Scholar 

  36. Knekt P, Aromaa A, Maatela J, et al. Vitamin E and cancer prevention. Am J Clin Nutr 1991; 53: 283s–6s.

    PubMed  CAS  Google Scholar 

  37. Goodman MT, Kolonel LN, Yoshizawa CN, Hankin JH. The effect of dietary cholesterol and fat on the risk of lung cancer in Hawaii. Am J Epidemiol 1988; 128: 1241–55.

    PubMed  CAS  Google Scholar 

  38. Knekt P, Seppänen R, Järvinen R, et al. Dietary cholesterol, fatty acids, and the risk of lung cancer among men. Nutr Cancer 1991; 16: 267–75.

    PubMed  CAS  Google Scholar 

  39. Heilbrun LK, Nomura AMY, Stemmermann GN. Dietary cholesterol and lung cancer risk among Japanese men in Hawaii. Am J Clin Nutr 1984; 39: 375–9.

    PubMed  CAS  Google Scholar 

  40. Chyou PH, Nomura AMY, Stemmermann GN, Kato I. Lung cancer: A prospective study of smoking, occupation, and nutrient intake. Arch Environ Health 1993; 48: 69–72.

    Article  PubMed  CAS  Google Scholar 

  41. Shekelle RB, Rossof AH, Stamler J. Dietary cholesterol and incidence of lung cancer: The Western Electric Study. Am J Epidemiol 1991; 134: 480–4.

    PubMed  CAS  Google Scholar 

  42. Hinds MW, Kolonel LN, Hankin JH, Lee J. Dietary cholesterol and lung cancer risk in a multiethnic population in Hawaii. Int J Cancer 1983; 32: 727–32.

    PubMed  CAS  Google Scholar 

  43. Goodman MT, Hankin JH, Wilkens LR, Kolonel, LN. High-fat foods and the risk of lung cancer. Epidemiology 1992: 3: 288–99.

    PubMed  CAS  Google Scholar 

  44. Gordon T, Kannel WB. Drinking and mortality. The Framingham Study. Am J Epidemiol 1984; 120: 97–107.

    PubMed  CAS  Google Scholar 

  45. Kono S, Ikeda M, Tokudome S, Nishizumi M, Kuratsune M. Alcohol and mortality: A cohort study of male Japanese physicians. Int J Epidemiol 1986; 15: 527–32.

    PubMed  CAS  Google Scholar 

  46. Stemmermann GN, Nomura AMY, Chyou PH, Yoshizawa C. Prospective study of alcohol intake and large bowel cancer. Dig Dis Sci 1990; 35: 1414–20.

    Article  PubMed  CAS  Google Scholar 

  47. Kabat GC, Wynder EL. Lung cancer in nonsmokers. Cancer 1984; 53: 1214–21.

    Article  PubMed  CAS  Google Scholar 

  48. Holst PA, Kromhout D, Brand R. For debate: pet birds as an independent risk factor for lung cancer. Br Med J 1988; 297: 1319–21.

    Article  CAS  Google Scholar 

  49. Restrepo HE, Correa P, Haenszel W, Brinton LA, Franco A. A case-control study of tobacco-related cancers in Colombia. Bull PAHO 1989; 23: 405–13.

    CAS  Google Scholar 

  50. Pierce RJ, Kune GA, Kune S, et al. Dietary and alcohol intake, smoking pattern, occupational risk, and family history in lung cancer patients: results of a case-control study in males. Nutr Cancer 1989; 12: 237–48.

    Article  PubMed  CAS  Google Scholar 

  51. Mettlin C. Milk drinking, other beverage habits, and lung cancer risk. Int J Cancer 1989; 43: 608–12.

    PubMed  CAS  Google Scholar 

  52. Hirayama T. Prospective studies on cancer epidemiology based on census population in Japan. In: Bucalossi P, Veronesi W, Cascinelle N, eds. Cancer Epidemiology: Environmental Factors. Proceedings of the Eleventh International Cancer Congress. Florence, Vol. 3. Amsterdam, The Netherlands: Exerpta Medica, 1974: 26–35.

    Google Scholar 

  53. Klatsky AL, Friedman GD, Siegelaub AB. Alcohol and mortality: A ten-year Kaiser-Permanente experience. Ann Intern Med 1981; 95: 139–45.

    PubMed  CAS  Google Scholar 

  54. Pollack ES, Nomura AMY, Heilbrun LK, Stemmermann GN, Green SB. Prospective study of alcohol consumption and cancer. N Engl J Med 1984; 310: 617–21.

    Article  PubMed  CAS  Google Scholar 

  55. Stockwell HG, Matanoski GM. Re: "Association of alcohol consumption and cancer." N Engl J Med 1984; 311: 256.

    Google Scholar 

  56. Stockwell HG, Matanoski GM. A case-control study of lung cancer in painters. J Occup Med 1985; 27: 125–6.

    PubMed  CAS  Google Scholar 

  57. Kvåle G, Bjelke E, Gart JJ. Dietary habits and lung cancer risk. Int J Cancer 1983; 31: 397–405.

    PubMed  Google Scholar 

  58. Byers T. Diet as a factor in the etiology and prevention of lung cancer. In: Jonathan M. Samet, ed. Epidemiology of Lung Cancer. New York, NY (USA): Marcel Dekker, Inc 1994: 335–52.

    Google Scholar 

  59. Marshall JR, Hastrup JL. Mismeasurement and the resonance of strong confounders: uncorrelated errors. Am J Epidemiol 1996; 143: 1069–78.

    PubMed  CAS  Google Scholar 

  60. Graham S, Zielezny M, Marshall J, et al. Diet in the epidemiology of postmenopausal breast cancer in the New York State Cohort. Am J Epidemiol 1992; 136: 1327–37.

    PubMed  CAS  Google Scholar 

  61. Harris RE, Zang EA, Anderson JE, Wynder EL. Race and sex differences in lung cancer risk associated with cigarette smoking. Int J Epidemiol 1993; 22: 592–9.

    PubMed  CAS  Google Scholar 

  62. Risch HA, Howe GR, Jain M, Burch JD, Hollowaty EJ, Miller AB. Are female smokers at higher risk for lung cancer than male smokers? A case-control analysis by histologic type. Am J Epidemiol 1993; 138: 281–93.

    PubMed  CAS  Google Scholar 

  63. Steinmetz KA, Potter JD. Vegetable, fruit, and cancer. I. Epidemiology. Cancer Causes Control 1991; 2:325–57.

    Article  PubMed  CAS  Google Scholar 

  64. Steinmetz KA, Potter JD. Vegetable, fruit, and cancer. II. Mechanisms. Cancer Causes Control 1991; 2: 427–42.

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Social and Preventive Medicine, State University of New York at Buffalo, Buffalo, USA

    Elisa V. Bandera, Jo L. Freudenheim, Maria Zielezny, Roger L. Priore, John Brasure & Saxon Graham

  2. Arizona Cancer Center, Tucson, USA

    James R. Marshall

  3. New York State Department of Health, Albany, USA

    Mark Baptiste

Authors
  1. Elisa V. Bandera
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  2. Jo L. Freudenheim
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  3. James R. Marshall
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  4. Maria Zielezny
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  7. Mark Baptiste
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  8. Saxon Graham
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Bandera, E.V., Freudenheim, J.L., Marshall, J.R. et al. Diet and alcohol consumption and lung cancer risk in the New York State Cohort (United States). Cancer Causes Control 8, 828–840 (1997). https://doi.org/10.1023/A:1018456127018

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