Journal of the American College of Cardiology
Volume 54, Issue 1, Supplement, 30 June 2009, Pages S20-S31
State-of-the-Art PaperCellular and Molecular Basis of Pulmonary Arterial Hypertension
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Key Words
pulmonary arterial hypertension
cellular
molecular basis
Abbreviations and Acronyms
ALK
activin-receptorlike kinase
Ang
angiopoeitin
BMP
bone morphogenetic protein
BMPR
bone morphogenetic protein receptor
cGMP
cyclic guanosine monophosphate
EC
endothelial cell
ECM
extracellular matrix
enMT
endothelial mesenchymal transition
eNOS
endothelial nitric oxide synthase
GTPase
guanosine triphosphatase
5-HT
hydroxytryptamine (serotonin)
5-HTT
hydroxytryptamine (serotonin) transporter
IPAH
idiopathic pulmonary arterial hypertension
MLC
myosin light chain
MLCK
myosin light chain kinase
MLCP
myosin light chain phosphatase
NO
nitric oxide
PA
pulmonary artery
PAEC
pulmonary artery endothelial cell
PAH
pulmonary arterial hypertension
PAI
plasminogen-activator inhibitor
PAK
p21-activated kinase
PASMC
pulmonary artery smooth muscle cell
PGI2
prostacyclin
PH
pulmonary hypertension
PK
protein kinase
ROCK
Rho kinase
SMC
smooth muscle cell
TGF
transforming growth factor
TRPC
canonical transient receptor potential
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Copyright © 2009 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.