Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Volume 1832, Issue 7, July 2013, Pages 1018-1027
ReviewCoagulation and coagulation signalling in fibrosis☆
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Highlights
► Introduce the key steps involved in the initiation of coagulation, coagulation signalling and fibrinolysis ► We review the evidence for the coagulation cascade in fibrosis of the lung, liver, kidney and heart. ► We summarise the opportunities and challenges of targeting the coagulation cascade in fibrosis.
Keywords
Fibrosis
Coagulation
Proteinase-activated receptor
Myofibroblast
Extracellular matrix
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This article is part of a Special Issue entitled: Fibrosis: Translation of basic research to human disease.
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