Original investigationComparison of Low-Dose CT and MR for Measurement of Intra-Abdominal Adipose Tissue: A Phantom and Human Study1
Section snippets
Phantom
A phantom was created to simulate the distribution of VAT and SAT in the abdomen. The phantom was constructed of an acrylic cylinder (diameter 20 cm; length 28 cm), airtight plastic bags (height 25 cm; width 15 cm), and latex balloons (diameter, 0.5–7 cm) filled with vegetable oil, normal saline, or air (Fig 1). The diameter and length along the z-axis of the phantom were 37 cm and 33 cm, respectively. The visceral fat compartment consisted of an oil-filled cylinder. Three round, saline-filled
Radiation Exposure in CT Scans
According to the manufacturer’s data, a small difference was found in the mean CTDIvol between phantom and volunteer studies that were acquired at the same kVp. This may be mostly attributable to the difference in the size of scanned objects. Mean effective doses to volunteers were estimated to be 14.3 ± 1.8 mSv at 140 kVp and 3.8 ± 0.6 mSv at 90 kVp. Thus with the assignment of a value of 100% to the radiation dose obtained at 140 kVp, the relative dose obtained at 90 kVp was 26.5% at a
Discussion
CT (10, 11, 12) and MR imaging (13, 14, 15) have been considered the most accurate and reproducible methods for directly assessing regional abdominal adipose tissue. One of the limitations of CT, however, is that it uses ionizing radiation. This characteristic of CT makes it unsuitable for longitudinal studies because the participants in obesity research may need to undergo repeated examinations over short intervals.
The results of our study using the phantom showed that it was possible to
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Supported by a grant no. 01-2007-09 from the Hallym University Medical Center Research Fund.