Pediatric tuberculosis: time for a new approach
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Role of PCR method using IS6110 primer in detecting Mycobacterium tuberculosis among the clinically diagnosed childhood tuberculosis patients at an urban hospital in Dhaka, Bangladesh
2018, International Journal of Infectious DiseasesCitation Excerpt :Furthermore, the commonly used tuberculin skin test (TST) frequently shows negative results among the malnourished group (Anderson et al., 2014; World Health Organization, 2013). Conventional culture using Lowenstein–Jensen (LJ) medium of gastric lavage or induced sputum specimens has a better diagnostic yield (20–40%) compared to microscopy, but takes 4–8 weeks for results (Berggren et al., 2004; Starke, 2003; Watterson and Drobniewski, 2000; Zar et al., 2005). Another culture method, the Mycobacterium Growth Indicator Tube (MGIT), has been shown in several studies to be a sensitive and quick technique for the rapid detection and isolation of Mycobacterium tuberculosis (MTB) and susceptibility testing, giving results within 2–27 days.
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