Advances in therapy for adult asthma

doi:10.1016/S1098-3597(08)80013-0

Clinical Cornerstone

Volume 8, Issue 4, 2008, Pages 62-75

https://doi.org/10.1016/S1098-3597(08)80013-0 Get rights and content

There are >22 million Americans with asthma. Chronic asthma is a worldwide problem with an increasing socioeconomic burden on individuals and on society. Recent advances have been made in diagnostic lung imaging, defining control of asthma, as well as in the education of patients with asthma. Accurate diagnosis of the cause of chronic cough in adults and of asthma in elderly individuals will help affected individuals receive appropriate treatment. Inhaled corticosteroids are the recommended first-line therapy for persistent asthma and can help prevent exacerbations in patients with asthma that are not well controlled. Early intervention and improved management can significantly reduce the socioeconomic burden of asthma. Patient education is an essential part of asthma management.

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Cited by (1)

Adherence to asthma management guidelines by middle-aged adults with current asthma
2009, Thorax
With the increasing burden of asthma worldwide, much effort has been given to developing and updating management guidelines. Using data from the Tasmanian Longitudinal Health Study (TAHS), the adequacy of asthma management for middle-aged adults with asthma was investigated.
Information about spirometry, medication history and current asthma status was collected by the most recent TAHS when participants were in their mid 40s. Only those who reported ever having asthma were eligible for analysis.
Of the 702 participants who reported ever having asthma, 50% had current asthma (n = 351) of whom 71% were categorised as having persistent asthma (n = 98 mild, n = 92 moderate, n = 58 severe). The majority (85.2%) of participants with current asthma had used some form of asthma medication in the past 12 months, but the proportion of the use of minimally adequate preventer medication was low (26%). Post-bronchodilator airflow obstruction increased progressively from mild to severe persistent asthma for those inadequately managed, but not for those on adequate therapy.
Appropriate use of asthma medication by this middle-aged group of adults with current asthma was inadequate, especially for those with adult-onset moderate or severe persistent disease and without a family history of asthma. These results suggest that proper use of preventer medication could protect against the progressive decline in lung function associated with increasing severity. This has implications not just for poor quality of life, but also for the development of fixed airflow obstruction.

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Advances in therapy for adult asthma

Am J Manag Care

Pulm Pharmacol Ther

Magn Reson Med

MMWR

Drugs

Curr Opin Allergy Clin Immunol

Chest

Hypertension

Clin Pract Epidemol Ment Health

Stroke

N Engl J Med

Respir Med

J Natl Med Assoc

Proc Am Thorac Soc

The burden of uncontrolled asthma on the US Health Care System

Manag Care

The natural history of asthma

J Allergy Clin Immunol

Asthma: Defining of the persistent adult phenotypes

Lancet

Advances in adult and pediatric asthma

J Allergy Clin Immunol

The mechanisms, diagnosis, and management of severe asthma in adults

Lancet