Elsevier

Respiratory Medicine

Volume 86, Issue 2, March 1992, Pages 121-124
Respiratory Medicine

Original Article
Inhaled steroids in patients with bronchiectasis

https://doi.org/10.1016/S0954-6111(06)80227-1Get rights and content

The effect of inhaled beclomethasone diproprionate (1500 μg day−1) on symptoms, pulmonary function andsputum production was examined in a double-blind, placebo-controlled, cross-over study in 20 patients with bronchiectasis. An 18% reduction in daily sputum production (P<0.003) was observed on treatment with inhaled steroid compared to placebo. A small, significant, improvement in morning peak expiratory flow rate (P<003) and forced expiratory volume in 1 s (P<0.03) was seen but the absolute changes are unlikely to be of clinical importance. Symptom scores for cough improved significantly (P<0.02). Inhaled steroids may have a role in the management of bronchiectasis by reducing cough and sputum production.

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