Evaluation of the Roche AMPLICOR™ MTB assay for the detection of Mycobacterium tuberculosis in sputum specimens from prison inmates☆
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2000, ChestCitation Excerpt :Most studies comparing different commercial amplification kits for therapid identification of MTB report no significant differences in testperformance.92324252627282930 The overall sensitivity of the, AMPLICOR assay in this study was low (culture, 61%; clinical PTB,44%) but was within the range of 33 to 87% reported in the literaturefor smear-negative PTB.23273031323334 It is higher than thesensitivity of 37% reported by Al-Zahrani et al35 in aprospective study of 357 patients suspected of having smear-negativePTB using an in-house PCR.
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This study was supported in part by an educational grant from Roche Diagnostic Systems.
Copyright © 1997 Published by Elsevier Inc.