Trends in Genetics
Volume 19, Issue 4, April 2003, Pages 169-172
Research FocusA new gene for asthma: would you ADAM and Eve it?
References (26)
Genomewide screen and identification of gene-gene interactions for asthma-susceptibility loci in three U.S. populations: collaborative study on the genetics of asthma
Am. J. Hum. Genet.
(2001)A second-generation genome-wide screen for asthma-susceptibility alleles in a founder population
Am. J. Hum. Genet.
(2000)A genome-wide search for linkage to asthma
Genomics
(1999)Genetic regulation of Dermatophagoides pteronyssinus-specific IgE responsiveness: a genome-wide multipoint linkage analysis in families recruited through 2 asthmatic sibs. Collaborative Study on the Genetics of Asthma (CSGA)
J. Allergy Clin. Immunol.
(1998)A major susceptibility gene for asthma maps to chromosome 14q24
Am. J. Hum. Genet.
(2002)Genome-wide search for atopy susceptibility genes in Dutch families with asthma
J. Allergy Clin. Immunol.
(2002)Extent and distribution of linkage disequilibrium in three genomic regions
Am. J. Hum. Genet.
(2001)Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness
Nature
(2002)Genetics of asthma and hay fever in Australian twins
Am. Rev. Respir. Dis.
(1990)A genetic study of immunoglobulin E
Am. J. Hum. Genet.
(1978)
A genome-wide search for quantitative trait loci underlying asthma
Nature
(1996)
Genome-wide linkage analyses of total serum IgE using variance components analysis in asthmatic families
Genet. Epidemiol.
(2001)
Genome screen for asthma and related phenotypes in the French EGEA study
Am. J. Respir. Crit. Care Med.
(2000)
Cited by (30)
Allele-specific transcription of the asthma-associated PHD finger protein 11 gene (PHF11) modulated by octamer-binding transcription factor 1 (Oct-1)
2011, Journal of Allergy and Clinical ImmunologyAutoimmunity in systemic lupus erythematosus: Integrating genes and biology
2006, Seminars in ImmunologyADAM33: A newly identified gene in the pathogenesis of asthma
2005, Immunology and Allergy Clinics of North AmericaADAM33 polymorphisms and phenotype associations in childhood asthma
2004, Journal of Allergy and Clinical ImmunologyCitation Excerpt :Given the initial findings of association and linkage among asthmatic subjects with airways hyperresponsiveness, it has been speculated that ADAM33 primarily influences airways hyperresponsiveness.24 However, because other ADAM proteins (ADAM10 and ADAM17) appear to interact with inflammatory cytokines (including TNF-α), it has been speculated that ADAM33 may also have important cytokine-stimulating effects.25 However, currently, the only evidence of ADAM33 as an important molecule in asthma pathogenesis is the linkage and association data.
Genetics of susceptibility to human helminth infection
2003, International Journal for ParasitologyGenetics of Asthma and Atopic Dermatitis
2009, Allergy and Allergic Diseases, Second Edition
Copyright © 2003 Elsevier Science Ltd. All rights reserved.