Elsevier

The Lancet

Volume 344, Issue 8923, 3 September 1994, Pages 656-660
The Lancet

Science and practice
Management of obstructive sleep apnoea/hypopnoea syndrome

https://doi.org/10.1016/S0140-6736(94)92089-3Get rights and content

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      CPAP is the most efficient therapy for maintaining upper-airway patency during sleep. CPAP treatment improves sleep architecture and oxygen saturation [29], and these factors contribute to the low levels of IGF-1 in OSA patients. Therefore, it is not unexpected that CPAP therapy could increase IGF-1 levels in OSA patients.

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      CPAP is an effective therapy for OSA, significantly reducing OSA symptoms in a vast majority of cases.17 Successful application of CPAP can dramatically improve the health-related quality of life of patients and transform somnolent individuals into energetic and more productive people.18 Unfortunately, many patients experience CPAP therapy as obtrusive, and the acceptance and long-term compliance of CPAP are typically poor.19

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