Original articleThe response to exercise in normal and asthmatic children
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Cited by (113)
Working Towards a Common Transatlantic Approach for Evaluation of Exercise-Induced Laryngeal Obstruction
2018, Immunology and Allergy Clinics of North AmericaExercise-induced bronchoconstriction update—2016
2016, Journal of Allergy and Clinical ImmunologyExhaled nitric oxide and other exhaled biomarkers in bronchial challenge with exercise in asthmatic children: Current knowledge
2015, Paediatric Respiratory ReviewsCitation Excerpt :Post-exercise symptoms such as cough, chest pain or dyspnea may be present, though the patient's and parents’ perception of these symptoms may be in contrast to results of the exercise challenge test [10,11]. EIB, which occurs in 70–90% of asthmatic children, is indicative of poor asthma control, but improves with appropriate asthma therapy [12–15]. A post-exercise FEV1 fall of at least 10% from baseline is diagnostic of EIB [9,16].
Approach to the Patient with Exercise-Induced Bronchoconstriction
2014, Middleton's Allergy: Principles and Practice: Eighth EditionAssessment of EIB. What You Need to Know to Optimize Test Results.
2013, Immunology and Allergy Clinics of North AmericaCitation Excerpt :This practice reduces the possibility of a false-positive result from recording a low FEV1 immediately at the end of exercise because of respiratory muscle fatigue.41 A decrease in the FEV1 of 10% and 15% from the baseline is close to the 95% confidence interval observed in healthy subjects in the laboratory42,43 and the field.5,44 A value of 13% has been reported to provide the optimal sensitivity (63%) and specificity (94%) for identifying children with asthma and young adults.45
Pathogenesis, prevalence, diagnosis, and management of exercise-induced bronchoconstriction: A practice parameter
2010, Annals of Allergy, Asthma and ImmunologyCitation Excerpt :Lowering the cutoff will result in an increased likelihood of false-positive test results for EIB, whereas raising the cutoff will result in the increased likelihood of false-negative test results for EIB. The ATS6 and the European Respiratory Society99 have recommended a 10% decrease in FEV1 after exercise as criterion for EIB, based on 2 standard deviations from the mean percentage decrease in FEV1 in healthy individuals.38 As noted above, it is essential to confirm the diagnosis of EIB using objective measures because of the lack of sensitivity and specificity of self-reported symptoms.
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Cystic Fibrosis Foundation Clinical Fellow.