Original articleMaternal smoking in early childhood: A risk factor for bronchial responsiveness to exercise in primary-school children†
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Side-stream tobacco smoke-induced airway hyperresponsiveness in early postnatal period is involved nerve growth factor
2016, Respiratory Physiology and NeurobiologyCitation Excerpt :Interestingly, the elevated pulmonary function and SP innervation in the PD2 group was attenuated by treatment with NGF-Ab before SS exposure, indicating that the increased SP innervation and altered lung function are regulated by NGF. Epidemiological studies show that the probability of developing or exacerbating childhood asthma increases in children of mothers who smoke cigarettes (Chilmonczyk et al., 1993; Frischer et al., 1992; Gilliland et al., 2003, 2000; Ronchetti et al., 1992; Weitzman et al., 1990 Yu et al., 2008). Our recent study showed that exposure to SS during early postnatal period increased the incidence of airway hyperreactivity in adult mice (Wu et al., 2009).
Effects of Environmental Tobacco Smoke during Early Life Stages
2014, The Lung: Development, Aging and the Environment: Second EditionPhysical, behavioral, and cognitive effects of prenatal tobacco and postnatal secondhand smoke exposure
2014, Current Problems in Pediatric and Adolescent Health CareCitation Excerpt :Postnatally, infancy appears to be the period associated with the highest risk of respiratory, neurological, and immunological morbidity.30,31 For example, the risk of bronchitis and pneumonia from SHS exposure is highest in infancy,15 and early postnatal SHS exposure is associated both with increased rates of hospitalization for respiratory illness and bronchial hyper-responsiveness during the first 6 months of life.32 As children get older, rates of such complications decrease, perhaps because of diminished exposure as they spend less time in the presence of parents and so have decreased SHS exposure.33
Housing and child health
2013, Current Problems in Pediatric and Adolescent Health CareCitation Excerpt :Postnatally, the risk of respiratory, neurological, and immunological morbidity appears to be highest during infancy because these systems are not fully developed at birth.75,88,89 The risk of bronchitis and pneumonia from SHS exposure peaks during the first year of life,75 and early postnatal exposure to SHS is associated with bronchial hyperresponsiveness and hospitalization for respiratory illness within the first 6 months of life.90 The rates of the these complications decline as children grow older, possibly because they spend less time in the home as they age, thereby decreasing SHS exposure.91
Smoking, environmental tobacco smoke, and aspirin-exacerbated respiratory disease
2012, Annals of Allergy, Asthma and ImmunologyDifferential Diagnosis in Allergy
2011, Otolaryngologic Clinics of North America
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Supported by a grant (No. 0701565 5) from the Bundesministerium f. Forschung und Technologie, Bonn, Germany.