Original article: general thoracicHeart-lung transplantation for Eisenmenger syndrome: early and long-term results
Section snippets
Patients and methods
A retrospective study of HLT was performed comparing the outcome of patients with ES with those receiving transplants for other indications. There have been no cases of bilateral-lung transplantation or single-lung transplantation for ES in our institution. The records of all patients who underwent HLT at Papworth Hospital between July 1984 and August 1999 were reviewed. Fifty-one patients with the clinical and operative diagnosis of ES were identified. A group formed by all 212 non-Eisenmenger
Results
The demographic characteristics and operative variables of the two groups are listed in Table 1. The cardiac anatomy of the ES patients is shown in Table 2. Patients with ES had similar age to non-ES at the time of transplantation (34.1 versus 32.8 years, p = 0.47). In the ES group, female sex (69% versus 46%, p = 0.005) and previous cardiothoracic operation (24% versus 11%, p = 0.012) were more prevalent.
There was no statistically significant difference in allograft ischemic times and
Comment
For many decades physicians caring for patients with ES have been frustrated by their inability to offer more than inadequate palliation. Even those cases followed up until recently in centers specializing in congenital heart disease had a life expectancy that rarely exceeded 40 years [1]. With the development of HLT, the outlook for these patients changed significantly, although with time it has been increasingly recognized that the benefits of transplantation for this group of patients are
Acknowledgments
Doctors Stoica and Satchithananda are supported by grants from the Garfield Weston Research Trust.
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