General paper
A comparative study on the effects of ascorbic acid deficiency and supplementation on endurance and mitochondrial oxidative capacities in various tissues of the guinea pig

https://doi.org/10.1016/0305-0491(86)90359-7Get rights and content

Abstract

  • 1.

    1. The aim of this study was to ascertain the effects of ascorbic acid deficiency and supplementation on endurance and mitochondrial oxidative capacities in various tissues of guinea pigs.

  • 2.

    2. Endurance capacity was significantly reduced by ascorbic acid deficiency and supplementation.

  • 3.

    3. Oxidative capacities were reduced in heart, liver and brown adipose tissue but it seems as if skeletal muscle is protected against ascorbic acid deficiency and supplementation-induced oxidative damage.

  • 4.

    4. Skeletal muscle and liver but not heart appear to be susceptible to exercise-induced oxidative damage.

  • 5.

    5. To a certain extent oxidative capacities could be related to the glutathione status in the various tissues.

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