Somatostatin and macrophage function: modulation of hydrogen peroxide, nitric oxide and tumor necrosis factor release
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Octreotide negates the benefit of galantide when used in the treatment of caerulein-induced acute pancreatitis in mice
2010, HPBCitation Excerpt :This may be an example of common receptor activity of these two peptides. Another reason for the decreased reduction in MPO activity seen with octreotide as well as with the combination of the two peptides may involve the contribution to MPO activity of activated monocytes and macrophages44 as octreotide has been shown to promote activation of the monocyte–macrophage system.45,46 Octreotide has also been shown to inhibit neutrophil chemotaxis induced by substance P.43
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