Lung Proteases

Effect of elexacaftor/tezacaftor/ivacaftor on airway and systemic inflammation in cystic fibrosis
Michelle Casey, Claudie Gabillard-Lefort, Oisín F McElvaney, Oliver J McElvaney, Tomás Carroll, Ronan C Heeney, Cedric Gunaratnam, Emer P Reeves, Mark P Murphy, Noel G McElvaney

Thorax Aug 2023, 78 (8) 835-839; DOI: 10.1136/thorax-2022-219943
Tracheostomy in children is associated with neutrophilic airway inflammation
Jason Powell, Steven Powell, Michael W Mather, Lauren Beck, Andrew Nelson, Pawel Palmowski, Andrew Porter, Jonathan Coxhead, Ann Hedley, Jonathan Scott, Anthony J Rostron, Thomas P Hellyer, Fatima Zaidi, Tracey Davey, James P Garnett, Rachel Agbeko, Chris Ward, Christopher J Stewart, Clifford C Taggart, Malcolm Brodlie, A John Simpson

Thorax Oct 2023, 78 (10) 1019-1027; DOI: 10.1136/thorax-2022-219557
Dysregulated fibulin-5 expression and elastogenesis in COPD lungs: pyromaniac or fire fighter?
Guy Brusselle

Thorax Jan 2015, 70 (1) 1-2; DOI: 10.1136/thoraxjnl-2014-205887
Untangling the protease web in COPD: metalloproteinases in the silent zone
Simon R Johnson

Thorax Feb 2016, 71 (2) 105-106; DOI: 10.1136/thoraxjnl-2015-208204
Relationship between pulmonary matrix metalloproteinases and quantitative CT markers of small airways disease and emphysema in COPD
Kristoffer Ostridge, Nicholas Williams, Viktoriya Kim, Michael Bennett, Stephen Harden, Lindsay Welch, Simon Bourne, Ngaire A Coombs, Paul T Elkington, Karl J Staples, Tom MA Wilkinson

Thorax Feb 2016, 71 (2) 126-132; DOI: 10.1136/thoraxjnl-2015-207428
Proteinase-activated receptors in fibroproliferative lung disease
Ricardo J José, Andrew E Williams, Rachel C Chambers

Thorax Feb 2014, 69 (2) 190-192; DOI: 10.1136/thoraxjnl-2013-204367
Proteolytic cleavage of elafin by 20S proteasome may contribute to inflammation in acute lung injury
Aoife Kerrin, Sinéad Weldon, Allen Hung-Kang Chung, Thelma Craig, A John Simpson, Cecilia M O'Kane, Danny Francis McAuley, Clifford C Taggart

Thorax Apr 2013, 68 (4) 315-321; DOI: 10.1136/thoraxjnl-2012-202536
Impaired lung repair during neutropenia can be reverted by matrix metalloproteinase-9
Jorge Blázquez-Prieto, Inés López-Alonso, Laura Amado-Rodríguez, Covadonga Huidobro, Adrián González-López, Wolfgang M Kuebler, Guillermo M Albaiceta

Thorax Apr 2018, 73 (4) 321-330; DOI: 10.1136/thoraxjnl-2017-210105
Mesenchymal stromal cells: a novel therapy for the treatment of chronic obstructive pulmonary disease?
Winifred Broekman, Padmini P S J Khedoe, Koen Schepers, Helene Roelofs, Jan Stolk, Pieter S Hiemstra

Thorax Jun 2018, 73 (6) 565-574; DOI: 10.1136/thoraxjnl-2017-210672
Cigarette smoke exposure and alveolar macrophages: mechanisms for lung disease
Sebastian T Lugg, Aaron Scott, Dhruv Parekh, Babu Naidu, David R Thickett

Thorax Jan 2022, 77 (1) 94-101; DOI: 10.1136/thoraxjnl-2020-216296

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Lung Proteases