Summary of current cancer-related symptom management guidelines in relation to common symptoms seen in MPM
| Symptom | Management | Reference literature |
| Breathlessness | Pleural fluid control | See ‘Pleural fluid management’ section |
| Sustained release morphine | 234 235 | |
| Breathing control and use of fans | 236–239 | |
| Pain | Opioids | 240 241 |
| Amitriptyline, duloxetine, gabapentin or pregabalin for neuropathic pain | 242 243 | |
| Radiotherapy for refractory localised pain | See ‘Radiotherapy’ section | |
| Fatigue | Aerobic exercise | 244 |
| Anorexia | Megestrol acetate | 245 |