Table 1

Effect of trial allocation on T1 and T2 smoking cessation

Quit smoking at T1 (n=1544)
Primary analysis*Yes (n=111)No (n=1433)Univariable OR (95% CI)Multivariable OR† (95% CI)
 Intervention, n (%)75 (68%)683 (48%)2.29 (1.52 to 3.45)2.38 (1.56 to 3.64)
 Control, n (%)36 (32%)750 (52%)
Sensitivity analysis‡Yes (n=111)No (n=895)Univariable OR (95% CI)Multivariable OR† (95% CI)
 Intervention, n (%)75 (68%)452 (50%)2.04 (1.34 to 3.10)2.09 (1.36 to 3.23)
 Control, n (%)36 (32%)443 (50%)
Quit smoking at T2 (n=1524)
Primary analysis*Yes (n=194)No (n=1330)Univariable OR (95% CI)Multivariable OR† (95% CI)
 Intervention, n (%)115 (59%)634 (48%)1.60 (1.18 to 2.17)1.60 (1.17 to 2.18)
 Control, n (%)79 (41%)696 (52%)
Sensitivity analysis‡Yes (n=194)No (n=671)Univariable OR (95% CI)Multivariable OR† (95% CI)
 Intervention, n (%)115 (59%)373 (55%)1.16 (0.84 to 1.61)1.16 (0.65 to 1.33)
 Control, n (%)79 (41%)298 (45%)
  • *Intention-to-treat (ITT) analyses with the imputed population.

  • †Adjusted for T0 cancer distress, recruitment site, gender, age, marital group, deprivation and experience of lung cancer.

  • ‡Complete case analyses.